| NCT02352077 | NeuroRegen Scaffold™ With Stem Cells for Chronic Spinal Cord Injury Repair | Chinese Academy of Sciences | | - Age 18 - 65 yrs
- Level C5-T12
AIS A- All
- be able and willing to make regular visits to the hospital for follow-up assessments.
- NOT have contraindications for MRI scanning, e.g. metal in body
| | 30 | PHASE1 | Biological/cell based | General health | - American Spinal Injury Association Impairment Scale (AIS)
- Bowel and bladder control
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Functional Independence Measure (FIM)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
- Motor Evoked Potentials (MEPs)
- Pain Visual Analog Scale (VAS)
- Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
| 12 months | 01 January 2015 | 02 February 2015 | 3 | |
| NCT02340910 | Dose-Response Effects of Whole Body Vibration on Spasticity and Walking in SCI | Shepherd Center, Atlanta GA | | - Age 16 - 72 yrs
- Level C1-T12
AIS A, B, C, D- ≥ 6 months
- be able to tolerate standing.
- have some spasticity in the leg muscles.
- be able to sit at the edge of a mat for 1 minute without assistance.
| Ended | 46 | NA | Technology | Spasticity | - Pendulum Test (Wartenberg)
- Spinal Cord Injury Spasticity Evaluation Tool (SCI-SET)
| 0 days | 02 February 2015 | 19 January 2015 | 1 | |
| NCT02339233 | Epi Stim to Facilitate Standing and Stepping | University of Louisville | | - Age 18 - 75 yrs
- Level C1-T9
AIS A, B, C- ≥ 1 years
- NOT be able to stand or step on own
- NOT have received botox in past 6 months
- NOT be taking medication for spasticity
| Ended | 8 | NA | Technology | Standing/walking/mobility | | 1 year | 01 January 2010 | 15 January 2015 | 1 | |
| NCT02331979 | Improving Bladder Function in SCI by Neuromodulation | University of California, Los Angeles | | - Age 18 - 45 yrs
- Level C2-T8
AIS A, B- ≥ 1 years
- have a neurogenic bladder requiring clean intermittent straight catheterization.
- NOT have received botox injection, or bladder surgery (suprapubic access, Brindley procedure, etc
- NOT have prostatic hypertrophy or bladder outlet disorder
| Recruiting | 24 | NA | Technology | Bladder health/function | | 48 months | 01 September 2015 | 06 January 2015 | 1 | |
| NCT02329652 | Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury | MetroHealth Medical Center | | - Age ≥ 17 yrs
- Level C4-C8
AIS A, B, C, D- ≥ 6 months
- able to move the muscles that bend the elbow.
- have no another implanted electrical device (e.g. pacemaker or ventilator).
| Recruiting | 30 | NA | Technology | Arm/hand function | - Grasp and Release Test (GRT)
| 0 days | 01 December 2014 | 31 December 2014 | 1 | |
| NCT02313194 | Spinal Cord Neuromodulation for Spinal Cord Injury | University of California, Los Angeles | | - Age ≥ 18 yrs
- Level C1-C5
AIS A, B- ≥ 1 years
- be unable to grip or move independently
- NOT have other implanted device, e.g. pacemaker
| Active | 12 | PHASE1, PHASE2 | Technology | Arm/hand function | | 24 months | 01 July 2013 | 09 December 2014 | 1 | |
