NeuroRegen Scaffold™ With Stem Cells for Chronic Spinal Cord Injury Repair

Biological/cell based
General health
Online since 2 November 2021, updated 947 days ago

About this trial

This trial is recruiting individuals with complete chronic spinal cord injuries to test the safety and effect of implanting a scaffold structure loaded with bone marrow cells or bone marrow-derived stem cells. The scaffold (NeuroRegen) provides a suitable growth environment for the cells. Participants will undergo spinal surgery for the implantation of the scaffold and cells into the spinal cord. Researchers will assess the safety of the procedure and measure whether it promotes neurological recovery. Note: This study is enrolling by invitation only.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C5 - T12
  • Severity (AIS)?
  • AIS-A
    Time since injury
    ≥ 1 month
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C5-T12
    Additionally, participants must
    be able and willing to make regular visits to the hospital for follow-up assessments.
    NOT have contraindications for MRI scanning, e.g. metal in body

    What’s involved

    Type

    Biological/cell based

    Details

    The total duration of the study is 12 months and will involve the following participant activities: Undergo spinal surgery for transplantation of the scaffold and cells into the injured spinal cord. Undergo comprehensive rehabilitation, psychological, and nutritional intervention after surgery. Participate in outcome assessments 6 months and 12 months after the surgery.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Bladder health/function

    Bowel health

    Mental health and psychosocial factors

    Pain

    Sensory function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 Jan 2015
    • Organisation
    • Chinese Academy of Sciences
    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 Jan 2015
    • Organisation
    • Chinese Academy of Sciences

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more