Spinal Cord Neuromodulation for Spinal Cord Injury

Technology
Arm/hand function
Online since 1 November 2021, updated 890 days ago

About this trial

This study is recruiting individuals with chronic cervical (neck area) spinal cord injuries to test the use of an implanted epidural stimulation device. Researchers want to see if the device is safe, and whether it can restore function. The device is surgically placed over the protective coating of the spinal cord in order to activate nerves that move the limbs. This study specifically targets the upper extremities to improve arm and hand function. Participants will receive surgery to implant the device; training will be completed over 24 months of followup. The study will also assess the effect of a drug (Buspirone) taken in combination with the stimulation.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - C5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    ≥ 1 year
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-C5
    Additionally, participants must
    be unable to grip or move independently
    NOT have other implanted device, e.g. pacemaker

    What’s involved

    Type

    Technology

    Details

    Surgery for the implantation of the stimulation device. Training and assessment in a follow-up of 24 months.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Active
    • Trial start date
    • 1 Jul 2013
    • Organisation
    • University of California, Los Angeles
    • Trial recruitment status
    • Active
    • Trial start date
    • 1 Jul 2013
    • Organisation
    • University of California, Los Angeles

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more