Epi Stim to Facilitate Standing and Stepping

Technology
Standing/walking/mobility
Online since 1 November 2021, updated 963 days ago

About this trial

This is a rehabilitation trial recruiting participants with chronic spinal cord injuries to test the use of a surgically implanted device that electrically stimulates the spinal cord (epidural stimulation) in combination with training for standing and stepping. Participants will start with 80 sessions of step/stand training, then will receive surgery to implant the electrical stimulation device over the spinal cord. Participants will continue stepping and standing with electrical stimulation turned on for 80-200 sessions. Researchers want to see if training results in better standing and stepping. Participants will be measured for the amount of time they are able to stand without manual assistance and also for the number of steps taken without manual assistance.

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - T9
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    1 year - 75 years
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-T9
    Additionally, participants must
    NOT be able to stand or step on own
    NOT have received botox in past 6 months
    NOT be taking medication for spasticity

    What’s involved

    Type

    Technology

    Details

    80 training sessions where the participant will practice standing and stepping with a harness that supports their body weight. Surgery to implant the electrical stimulation device into the body. 80-200 training sessions where the participant will practice standing and stepping in a harness that supports their body weight with electrical stimulation to the spinal cord.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jan 2010
    • Organisation
    • University of Louisville
    • Trial recruitment status
    • Ended
    • Trial start date
    • 1 Jan 2010
    • Organisation
    • University of Louisville

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more