| NCT05726591 | Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders | National Institutes of Health Clinical Center (CC) | | - Age 3 - 17 yrs
- Level C1-S5
AIS C, D- All
- be able to walk at least 10 feet without stopping with or without a walking aid
- have an impairment of knee movement that affects walking
| Recruiting | 44 | NA | Rehabilitation | Standing/walking/mobility | | 36 weeks | 02 May 2023 | 14 February 2023 | 1 | |
| NCT05669508 | Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity | Thomas Jefferson University | | - Age 18 - 55 yrs
- Level C2-T10
AIS B, C, D- ≥ 12 months
| Active | 4 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- American Spinal Injury Association Impairment Scale (AIS)
- Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Spinal Cord Independence Measure (SCIM)
| 3 Months | 10 February 2022 | 03 January 2023 | 1 | |
| NCT05465486 | NeuroSuitUp: Neurorehabilitation Through Synergistic Man-machine Interfaces | Aristotle University Of Thessaloniki | | - Age ≥ 14 yrs
- Level C1-C8
AIS A, B, C, D, E- All
- NOT have Other neurological condition that has a possibility to significantly affect the neurological status of the participants (or) the ability to control a BCI (or) the neurophysiological recordings
- NOT have multiple sclerosis
- NOT have amyotrophic lateral sclerosis
- NOT have parkinson's disease
- NOT have refractory epilepsy
- NOT have cardiac deficiency
- NOT have pulmonary deficiency
| By invitation | 20 | NA | Technology | Arm/hand function | - Spinal Cord Independence Measure (SCIM)
| 1 year | 01 February 2027 | 19 July 2022 | 1 | |
| NCT05423600 | Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia | Virginia Commonwealth University | | - Age 18 - 70 yrs
- Level C1-C8
AIS B, C, D- ≥ 1 years
- Have visible muscle contraction in response to neuromuscular electrical stimulation of the wrist extensor muscles
- Have a companion that can assist the participant with research activities throughout the study
- Possess appropriate technology to enable telehealth participation in the trial (web camera, computer, microphone, speakers, high-speed broadband internet connection, telephone number)
- Not have an implanted stimulator
| Recruiting | 44 | NA | Technology | Arm/hand function | - Electromyography
- Hand-Held Myometery / Dynamometry
- Spinal Cord Injury Functional Index
| 20 weeks | 15 June 2022 | 21 June 2022 | 4 | |
| NCT05544175 | NEUROMOdulation Pain Therapy in Combination With Intensive Physiotherapy | Charles University, Czech Republic | Single Group Assignment | - Age 18 - 60 yrs
- Level T1-S5
AIS C, D- All
- Have a spinal cord lesion resulting in spastic paraparesis (weakness of the lower extremities)
- Not have any other neurological condition
| Recruiting soon | 10 | Not Applicable | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- Spinal Cord Independence Measure (SCIM)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
- World Health Organization Disability Assessment Schedule II (WHODAS 2.0)
| 12 months | 01 October 2024 | 16 September 2022 | 1 | |
| NCT05630235 | Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI | University of Miami | | - Age 18 - 64 yrs
- Level C1-S5
AIS A, B, C, D- All
- NOT have psychopathology
- NOT have presence of significant medical illness
- have had continuous neuropathic pain for three months
| Ended | 6 | PHASE1, PHASE2 | Drug | Pain | - International Spinal Cord Injury Pain Classification (ISCIP)
- Numeric Pain Rating Scale
- Quantitative Sensory Testing (QST)
| 3 hours | 16 June 2025 | 29 November 2022 | 1 | |
