Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

Technology
General health
Online since 31 August 2023, updated 178 days ago

About this trial

This trial is including individuals with acute spinal cord injuries (within 7-30 days of injury) to test the effect of transcutaneous spinal cord stimulation (TSCS) on blood pressure. TSCS is a technique for stimulating the spinal cord via surface stimulation to modify spinal cord function. If included, participants will undergo two days of stimulation mapping followed by two days of orthostatic tests (lying on a bed that starts out flat and then moved into an upright seated position by raising the head of bed by 90° and dropping the base of the bed by 90° from the knee) one day with TSCS and one with sham stimulation. Final testing of blood pressure and orthostatic symptoms will be performed after 2 weeks.

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - T2
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    7 days - 30 days
    Healthy volunteers
    No
    C1-T2

    What’s involved

    Type

    Technology

    Details

    - participants will undergo orthostatic tests (lying on a bed that starts out flat and then moved into an upright seated position by raising the head of bed by 90° and dropping the base of the bed by 90° from the knee) - participants will receive one day with TSCS and one day with sham stimulation during orthostatic tests - Final testing of blood pressure and orthostatic symptoms will be performed after 2 weeks.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Pain

    Skin health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jun 2023
    • Organisation
    • Kessler Foundation
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Jun 2023
    • Organisation
    • Kessler Foundation

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more