Autologous Bone Marrow Stem Cell Transplantation in Patients With Subacute Spinal Cord Injury

About this trial

This trial is enrolling 40 individuals with subacute (3-6 months post injury), complete thoracic or lumbar spinal cord injuries (paraplegia) to test the safety and effectiveness of transplanted stem cells. The stem cells (autologous) are harvested and processed from each participant’s bone marrow, limiting an immune rejection response. If included, participants will either undergo: 1) spinal surgery to expose the spinal cord, followed by the injection of the stem cells into the injured spinal cord and surrounding spinal fluid; or 2) placebo injection under the skin. Both groups will receive two injections, separated by 90 days. Final testing of neurological function will be performed after one year.