| NCT00623389 | Evaluation of an Advanced Lower Extremity Neuroprostheses | Case Western Reserve University | | - Age 21 - 75 yrs
- Level C6-T12
AIS A, B, C- 6 months - 75 years
- NOT have another implanted device (e.g., pacemaker)
| Recruiting | 10 | NA | Technology | Standing/walking/mobility | | 1 year | 01 June 2018 | 26 February 2008 | 2 | |
| NCT06238492 | A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI | Kessler Foundation | | - Age 18 - 59 yrs
- Level C1-S5
AIS - ≤ 6 months
| Recruiting | 24 | NA | Psychosocial/other | General health | | 25 weeks | 01 April 2024 | 02 February 2024 | 3 | |
| NCT06233656 | Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries | University of South Florida | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
- NOT have a diagnosis with bipolar disorder or psychotic disorder
| Active | 140 | NA | Psychosocial/other | Mental health and psychosocial factors | - Generalized Anxiety Disorder (GAD-7)
- Patient Health Questionnaire-9 (PHQ-9)
- Perceived Stress Scale - 14 (PSS-14)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 2 months | 30 April 2024 | 31 January 2024 | 2 | |
| NCT06243952 | Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb Rehabilitation | Ecole Polytechnique Fédérale de Lausanne | | - Age 18 - 60 yrs
- Level C1-T10
AIS A, B, C, D- ≥ 12 months
- NOT have history of epilepsy
- NOT have previously been injected with stem cells in the spinal cord
- NOT be implanted with a device such as pacemakers or defibrillators
| Recruiting | 3 | NA | Surgery | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- Pain Numeric Rating Scale (NRS)
- Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
- Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI)
- Surface Electromyography (sEMG)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 1 year | 03 May 2024 | 06 February 2024 | 1 | |
| NCT06244160 | High Flow Oxygen Therapy After Spinal Cord Injury | Cardiff and Vale University Health Board | | - Age ≥ 18 yrs
- Level C4-T4
AIS A, B, C, D- ≤ 48 null
| Recruiting | 30 | NA | Technology | General health | | 10 days | 01 April 2024 | 06 February 2024 | 1 | |
| NCT06243211 | Spinal Decompression Plus Nerve Graft Implantation Following TSCI | University of Kentucky | | - Age 18 - 80 yrs
- Level C2-T12
AIS A, B- ≤ 48 null
| Recruiting | 10 | NA | Surgery | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Spinal Cord Independence Measure (SCIM)
| 1 year | 19 April 2024 | 06 February 2024 | 1 | |
