Neuromodulation as an Anti-inflammatory Treatment in SCI

Technology
General health
Online since 19 March 2024, updated 20 days ago

About this trial

This trial is enrolling 30 individuals with spinal cord injuries to test the anti-inflammatory effect of transcutaneous (skin surface) auricular vagus nerve stimulation (taVNS) vs sham taVNS. If included, participants will perform a single one-hour session of either: 1) taVNS intervention; or 2) sham intervention with blood draws prior to intervention, immediately following the intervention, and 24 hours following intervention. Investigators will measure the effect of vagus nerve stimulation on pro-inflammatory indicators (biomarkers) in blood tests.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have implanted device, e.g., pacemaker.

    What’s involved

    Type

    Technology

    Details

    - participants will perform a single 1-hour session of either 1) taVNS intervention or 2) sham intervention with blood draws prior to intervention, immediately following the intervention, and 24 hours following intervention.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Apr 2023
    • Organisation
    • Lawson Health Research Institute
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Apr 2023
    • Organisation
    • Lawson Health Research Institute

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more