Neuromodulation as an Anti-inflammatory Treatment in SCI

Technology

General health

Online since 19 March 2024, updated 119 days ago

About this trial

This trial is enrolling 30 individuals with spinal cord injuries to test the anti-inflammatory effect of transcutaneous (skin surface) auricular vagus nerve stimulation (taVNS) vs sham taVNS. If included, participants will perform a single one-hour session of either: 1) taVNS intervention; or 2) sham intervention with blood draws prior to intervention, immediately following the intervention, and 24 hours following intervention. Investigators will measure the effect of vagus nerve stimulation on pro-inflammatory indicators (biomarkers) in blood tests.

Included participants

Gender

All

Age

≥ 18 years

Injury level

C1 - S5

Severity (AIS)?

Time since injury

All

Healthy volunteers

C1-S5

Additionally, participants must

NOT have implanted device, e.g., pacemaker.

What’s involved

Type

Technology

Details

- participants will perform a single 1-hour session of either 1) taVNS intervention or 2) sham intervention with blood draws prior to intervention, immediately following the intervention, and 24 hours following intervention.

Potential benefits

Main benefits

General health

Additional benefits

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

Wings for Life supports SCITrialsFinder

Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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