Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis

Drug
Pain
Online since 19 March 2024, updated 93 days ago

About this trial

This trial is enrolling 558 individuals with chronic pain due to central nervous system disorders to test the effect and tolerability of a drug, AP707, on pain. This drug modifies certain neurotransmitters (endocannabinoids) that regulate key bodily functions. If included, participants will receive either AP707 or placebo over the course of 14 weeks. Changes in pain intensity, quality of life, sleep quality, and other measures will be monitored during the study. Final testing will be performed after 52 weeks.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-S5
    Additionally, participants must
    NOT have a history of addiction.
    understand German.

    What’s involved

    Type

    Drug

    Details

    - participants will receive either AP707 or placebo over the course of 14 weeks as an add-on to the standard of care. - Changes in pain intensity, quality of life and sleep and others measures are monitored through different scales to assess the efficacy of AP707 on chronic pain. - Final testing will be performed after 52 weeks.

    Potential benefits

    Main benefits

    Pain

    Additional benefits

    General health

    Mental health and psychosocial factors

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 2 Nov 2023
    • Organisation
    • Apurano Pharmaceuticals GmbH
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 2 Nov 2023
    • Organisation
    • Apurano Pharmaceuticals GmbH

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more