| NCT03989440 | AXER-204 in Participants With Chronic Spinal Cord Injury | ReNetX Bio, Inc. | | - Age 18 - 65 yrs
- Level C1-C8
AIS A, B, C, D- 1 years - 65 years
- have a spinal cord injury for at least 1 year.
- have a cervical spinal cord injury.
- have “serious” neurological deficits in upper extremity motor function (upper extremity motor score between 4-36 out of 50).
- be between the ages of 18 and 65 years.
| Ended | 52 | PHASE1, PHASE2 | Drug | General health | | | 16 July 2019 | 18 June 2019 | 6 | |
| NCT03965299 | Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury | University of Zurich | | - Age ≥ 18 yrs
- Level C1-T12
AIS A, B, C, D- ≤ 40 days
| Recruiting | 114 | NA | Technology | Bladder health/function | | | 19 June 2019 | 29 May 2019 | 4 | |
| NCT03966794 | Functional Scaffold Transplantation Combined With Epidural Electrical Stimulation for Spinal Cord Injury Repair | Chinese Academy of Sciences | | - Age 18 - 60 yrs
- Level C5-L1
AIS A- ≤ 60 years
- have had a spinal cord injury either within the last 14 days or for at least 6 months.
- have a neurological level of injury between C4- T12/L1.
- have an ASIA impairment scale (AIS) A: complete; no feeling or movement below the injury.
- be between the ages of 18 and 60 years.
| | 9 | PHASE1, PHASE2 | Surgery | Standing/walking/mobility | | | 01 August 2019 | 29 May 2019 | 1 | |
| NCT03935724 | Stem Cells in Spinal Cord Injury | Neuroplast | | - Age 18 - 65 yrs
- Level C6-T12
AIS A, B, C- 6 weeks - 8 weeks
- have had a spinal cord injury for 6-8 weeks.
- have a neurological level of injury between C6 and T12.
- have one of the following ASIA impairment Scale (AIS:
- AIS A: complete; no feeling or movement below the injury.
- AIS B: incomplete; have feeling, but no movement, below the injury.
- AIS C: incomplete; at least some feeling and mostly weak movement below the injury.
- be between the ages of 18-65 years.
| | 16 | PHASE2, PHASE3 | Biological/cell based | General health | | | 18 January 2022 | 02 May 2019 | 2 | |
| NCT03911492 | Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study | University of British Columbia | | - Age ≥ 17 yrs
- Level C1-T12
AIS A, B, C- ≤ 24 hours
- have had spinal cord injury within 24 hours.
- have a neurological level of injury between C0 and T12.
- have one have one of the following ASIA impairment scale (AIS):
- AIS A: complete; no feeling or movement below the injury
- AIS B: incomplete; have feeling, but no movement, below the injury
- AIS C: incomplete; at least some feeling and mostly weak movement below the injury
- be at least 17 years of age
| | 100 | NA | Drug | General health | | | 31 August 2019 | 11 April 2019 | 8 | |
| NCT03924388 | Spinal Cord Stimulation and Autonomic Response in People With SCI. | University of Calgary | | - Age 18 - 75 yrs
- Level C1-T6
AIS A, B- ≥ 1 years
- have a spinal cord injury for at least 1 year and at least 6 months from any spinal surgery.
- have a neurological injury between C1- T6.
- have one of the following ASIA impairment scale (AIS):
- AIS A: complete; no feeling or movement below the injury.
- AIS B: incomplete; have feeling, but no movement, below the injury.
- some strength in arm muscles (deltoids and biceps) on both sides.
- be between the ages of 18 and 65 years (22-65 years for the eSCS group).
- have already undergone electrode implantation surgery (only for the eSCS group).
| | 46 | NA | Technology | General health | | | 01 February 2020 | 23 April 2019 | 2 | |
