The Impact of Electroacupuncture on Clinical Effect,Brain Structural and Functional Changes on Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 31 May 2022, updated 678 days ago

About this trial

This trial is enrolling individuals with incomplete spinal cord injuries to test the effects of electroacupuncture (a form of acupuncture) on brain structure and functional recovery. Electroacupuncture passes a small electric current between pairs of acupuncture needles. Previous clinical studies of acupuncture have not looked at changes in the brain, which is closely related to the structure and function of spinal cord. The aim of this study is to aanyze changes in the brain, and to provide a theoretical basis for the clinical application of electroacupuncture. If included in the study, participants will be randomly assigned to one of two study groups; 1) receiving routine rehabilitation training, or 2) receiving rehabilitation training combined with electroacupuncture for 3 months. Rehabilitation will include training for sitting, standing, muscle strength, functional movement, and transfer training. The electroacupuncture will be performed with the HANS100A device on major acupoints (Jiaji points).

Included participants

Gender
All
Age
18 - 55 years
Injury level
C1 - C8
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    14 days - 30 days
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-C8
    Additionally, participants must
    be right-handed
    have some but not full muscle strength of both lower limbs
    be able to undergo magnetic resonance imaging (MRI)

    What’s involved

    Type

    Technology

    Details

    Rehabilitation training: Functional movement training and transfer training will be performed for 20min each time and once a day; Standing and walking training, 2 times a day, 30min each time. Electroacupuncture: Han's pain irritant instrument (HANS100A) for 30min with the stimulation frequency of 2 /100 Hz and intensity of 1-2mA. Once a day, 5 days a week and rest 2 days, a week is one course and the duration need 12 courses. Overall 3 months of intervention, and a follow-up assessment 3 months post-intervention Magnetic resonance imaging (MRI) before the study and after 3 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    Bladder health

    Bowel health

    General health

    Mental health

    Pain

    Sensory function

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Unknown
    • Trial start date
    • 26 Nov 2019
    • Organisation
    • The Third Affiliated hospital of Zhejiang Chinese Medical University
    • Trial recruitment status
    • Unknown
    • Trial start date
    • 26 Nov 2019
    • Organisation
    • The Third Affiliated hospital of Zhejiang Chinese Medical University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more