| NCT05544175 | NEUROMOdulation Pain Therapy in Combination With Intensive Physiotherapy | Charles University, Czech Republic | Single Group Assignment | - Age 18 - 60 yrs
- Level T1-S5
AIS C, D- All
- Have a spinal cord lesion resulting in spastic paraparesis (weakness of the lower extremities)
- Not have any other neurological condition
| Recruiting soon | 10 | Not Applicable | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- Spinal Cord Independence Measure (SCIM)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
- World Health Organization Disability Assessment Schedule II (WHODAS 2.0)
| 12 months | 01 October 2024 | 16 September 2022 | 1 | |
| NCT05630235 | Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI | University of Miami | | - Age 18 - 64 yrs
- Level C1-S5
AIS A, B, C, D- All
- NOT have psychopathology
- NOT have presence of significant medical illness
- have had continuous neuropathic pain for three months
| Recruiting | 20 | PHASE1, PHASE2 | Drug | Pain | - International Spinal Cord Injury Pain Classification (ISCIP)
- Numeric Pain Rating Scale
- Quantitative Sensory Testing (QST)
| 3 hours | 16 June 2025 | 29 November 2022 | 1 | |
| NCT05217498 | Combining Low Oxygen Therapy and an Adenosine A2a Receptor Antagonist to Improve Functional Mobility After Spinal Cord Injury | Spaulding Rehabilitation Hospital | | - Age 18 - 75 yrs
- Level C2-T12
AIS C, D- ≥ 12 months
- have the ability to advance one step overground without human assistance
| Recruiting soon | 40 | PHASE1, PHASE2 | Drug | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Timed Up and Go Test (TUG)
| 20 days | 01 September 2027 | 01 February 2022 | 1 | |
| NCT05333770 | Repetitive Transcranial Magnetic Stimulation to Promote Regeneration in Persons With SCI | Kessler Foundation | | - Age 18 - 55 yrs
- Level C2-C6
AIS A, B, C, D- All
- NOT have metal in the skull
- NOT have a pacemaker
- NOT have a history or seizures or brain injury
| | 20 | NA | Technology | Arm/hand function | - Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
| 6 months | 20 August 2022 | 19 April 2022 | 1 | |
| NCT05643313 | Clinical Investigation on Feasibility and Usability of the ABLE Exoskeleton Device for Individuals With Spinal Cord Injury to Perform Skills for Home and Community Environments | ABLE Human Motion S.L. | | - Age 18 - 70 yrs
- Level C5-L5
AIS A, B, C, D- ≥ 6 months
| Ended | 10 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0)
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 11 weeks | 25 November 2022 | 08 December 2022 | 2 | |
| NCT05700942 | AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI | University of Florida | | - Age 18 - 65 yrs
- Level C1-T12
AIS C, D- ≥ 1 years
- be able to walk 3 meters with or without devices, braces, or assistance of one person
- NOT have diagnosis of other neurologic condition
| Recruiting | 18 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- H reflex
| 8 weeks | 10 March 2023 | 26 January 2023 | 1 | |
