| NCT05622994 | Effects of CB1 Antagonist/Reverse Agonist Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury | Hospital Nacional de Parapléjicos de Toledo | | - Age 18 - 75 yrs
- Level C4-L1
AIS C, D- ≥ 1 years
- NOT have severe bone, kidney, or liver dysfunction
- NOT have hypothyroidism
| | 80 | PHASE2 | Drug | General health | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Ashworth and Modified Ashworth Scale (MAS)
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Fatigue Severity Scale (FSS)
- Hospital Anxiety and Depression Scale (HADS)
- Numeric Pain Rating Scale
- Penn Spasm Frequency Scale (PSFS)
- Spinal Cord Independence Measure (SCIM)
| 120 days | 01 November 2022 | 21 November 2022 | 1 | |
| NCT05757830 | PURO - PUlmonary Rehabilitation With O-RAGT Platform | Fondazione Don Carlo Gnocchi Onlus | | - Age 18 - 90 yrs
- Level T2-S5
AIS B, C, D- All
- Able to use a walker.
| Ended | 20 | NA | Technology | Standing/walking/mobility | | 48 hours | 23 December 2022 | 07 March 2023 | 4 | |
| NCT05646810 | Impact of Peripheral Afferent Input on Central Neuropathic Pain | University of Aarhus | | - Age 18 - 80 yrs
- Level C1-T12
AIS A, B, C, D- ≥ 1 years
| | 20 | NA | Drug | Pain | - Numeric Pain Rating Scale
| 95 minutes | 01 December 2022 | 12 December 2022 | 0 | |
| NCT05705453 | Epidural Stimulation After Neurologic Damage: Long-Term Outcomes | University of Minnesota | | - Age ≥ 22 yrs
- Level C5-S5
AIS A, B- ≥ 1 years
- HAVE an existing and functional implanted spinal cord stimulator system that is FDA approved
- NOT have current or anticipated need for opioid pain medication preventing participation in the rehabilitation program
- NOT have received Botox injections in the last six months
| Recruiting | 50 | NA | Technology | Arm/hand function | - Surface Electromyography (sEMG)
| 10 years | 01 March 2023 | 30 January 2023 | 1 | |
| NCT03898804 | An Early Feasibility Study of the ReHAB System | University Hospitals Cleveland Medical Center | Single Group Assignment | - Age 22 - 65 yrs
- Level C1-C8
AIS - ≥ 12 months
- Be at least 12 months post onset of tetraplegia.
- Not have an implanted stimulator (e.g. pacemaker or stimulators (of the spinal cord, deep brain, vagus nerve), cochlear implant, or defibrillator.
- Not be ventilator dependent.
| Recruiting | 12 | Not Applicable | Technology | General health | - Grasp and Release Test (GRT)
- Lawton Instrumental Activities of Daily Living scale (IADL)
| 13 months | 09 April 2019 | 02 April 2019 | 1 | |
| NCT05601661 | Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury | The University of Texas Health Science Center, Houston | | - Age ≥ 18 yrs
- Level C1-C8
AIS B, C, D- ≥ 12 months
- NOT have prior history of vagus nerve injury
| Ended | 6 | NA | Technology | Arm/hand function | - Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Spinal Cord Independence Measure (SCIM)
- Toronto Rehabilitation Institute Hand Function Test
| 132 days after enrollment | 15 June 2023 | 01 November 2022 | 1 | |
