| NCT07002437 | Hypoxia Pathways for Early Recovery After Spinal Cord Injury | University of Florida | | - Age 18 - 70 yrs
- Level C1-T6
AIS A, B, C, D- 1 months - 6 months
| Recruiting | 18 | NA | Drug | General health | - Hand-Held Myometery / Dynamometry
| 3 days | 20 November 2025 | 03 June 2025 | 2 | |
| NCT06976229 | Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial | XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd. | | - Age 18 - 65 yrs
- Level C4-L2
AIS A, B, C- 14 days - 60 days
| Recruiting | 12 | PHASE1 | Biological/cell based | General health | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS)
- Feasibility
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Spinal Cord Independence Measure (SCIM)
| 1 year | 02 July 2025 | 16 May 2025 | 1 | |
| NCT06723561 | Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury | Medical College of Wisconsin | | - Age ≥ 18 yrs
- Level C1-T12
AIS - ≥ 6 months
- experience central neuropathic pain, based on evaluation by a Physical medicine and rehabilitation physician
| Recruiting | 10 | PHASE2 | Drug | Mental health and psychosocial factors | - Neuropathoc Pain Symptom Inventory (NPSI)
- Quality of Life Index (QLI) - SCI Version
| 12 weeks | 01 February 2025 | 09 December 2024 | 1 | |
| NCT06838637 | Transcutaneous Spinal Cord Stimulation Home Study | University of British Columbia | | - Age 19 - 70 yrs
- Level C1-T6
AIS A, B- ≥ 1 years
- NOT have an intrathecal baclofen pump
- NOT have any implanted metal (other than dental implants) in the skull or presence of pacemakers, stimulators, or medication pumps in the trunk
- NOT have undergone electrode implantation surgery
| Recruiting | 6 | NA | Technology | General health | - Adverse Events (AEs)
- Blood Pressure and Heart Rate Regulation
- Surface Electromyography (sEMG)
| 10 weeks | 15 February 2024 | 20 February 2025 | 1 | |
| NCT06700304 | CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices | Neuralink Corp | | - Age ≥ 19 yrs
- Level C1-T1
AIS B- ≥ 12 months
- NOT have an active implanted devices
- Not require an MRI during the study
| Recruiting | 6 | NA | Technology | General health | - Adverse Events (AEs)
- Generalized Anxiety Disorder (GAD-7)
- Patient Health Questionnaire-9 (PHQ-9)
| 6 years | 20 November 2024 | 21 November 2024 | 1 | |
| NCT07036107 | A Trial on the Clinical and Socioeconomic Impact of Wearable Exoskeletons for Spinal Cord Injury Rehabilitation in the Spanish Healthcare System | ABLE Human Motion S.L. | | - Age 18 - 70 yrs
- Level C5-L5
AIS A, B, C, D- ≤ 6 months
| Recruiting | 80 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 2 Minute Walk Test
- 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS)
- Ashworth and Modified Ashworth Scale (MAS)
- Blood Pressure and Heart Rate Regulation
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- Spinal Cord Assessment Tool for Spastic Reflexes (SCATS)
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 4 months | 15 January 2026 | 25 June 2025 | 2 | |
