A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton.

Drug
General health
Online since 4 September 2025, updated 98 days ago

About this trial

This trial is enrolling 10 participants with traumatic spinal cord injury to test the safety of a drug (andecaliximab) designed to prevent abnormal bone growth in soft tissues such as muscles and tendons. If included, participants will receive weekly subcutaneous injections of andecaliximab for 8 weeks. Final testing of safety will be performed after 13 weeks.

Included participants

Gender
All
Age
18 - 89 years
Injury level
C1 - S5
  • Severity (AIS)?
  • Time since injury
    ≥ 10 days
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C1-S5

    What’s involved

    Type

    Drug

    Details

    - Participants will receive 8 weekly subcutaneous injections of andecaliximab. - Andecaliximab is a drug designed to prevent abnormal bone growth in soft tissues like muscles and tendons, which can occur after a spinal cord injury. - Final testing of safety will be performed after 13 weeks.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Bone health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more


    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 14 May 2025
    • Organisation
    • Ashibio Inc
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 14 May 2025
    • Organisation
    • Ashibio Inc

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more