| NCT05708274 | Pharmacological Agents for Chronic Spinal Cord Injury (SCI) | Bronx VA Medical Center | | - Age 18 - 65 yrs
- Level C1-C8
AIS - ≥ 12 months
- NOT have history of moderate to severe head trauma
- NOT have other neurological injury
- NOT have implanted stimulator, pacemaker, etc.
- have motor incomplete injury
- be able to perform thunb-index pinch
| Ended | 25 | PHASE1 | Drug | Arm/hand function | - Blood Pressure and Heart Rate Regulation
- Box and Block Test (BBT)
- Hand-Held Myometery / Dynamometry
- Nine Hole Peg Test
| 10 min after intervention | 20 January 2023 | 01 February 2023 | 2 | |
| NCT05968352 | Restoration of Bladder Function in Spinal Cord Injury | University of Oxford | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B- All
- have undergone implantation of a Finetech Brindley Bladder controller, with or without sacral posterior rhizotomy
- NOT have undergone external urethral sphincterotomy
| Ended | 0 | | Technology | Bladder health/function | | 3 hours | 18 November 2021 | 01 August 2023 | 1 | |
| NCT05966896 | Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury | University of Colorado, Denver | | - Age ≥ 18 yrs
- Level C7-T8
AIS B- ≥ 6 months
- NOT be shorter than 5'1" or taller than 6'3"
- NOT have unstable cardiorespiratory issues
| Recruiting soon | 2 | NA | Technology | Standing/walking/mobility | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 8 months | 01 August 2025 | 01 August 2023 | 0 | |
| NCT05970367 | Intensive Motor Rehabilitation With Technology for Patients With Central Neurological Disease | KU Leuven | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- ≥ 3 months
- be able to initiate movements against gravity
- NOT have severe visual impairment, communication, cognitive and language formation problems
- be at least 3 months post discharge from hospital/rehabilitation center, living at home
| Ended | 102 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Action Research Arm Test (ARAT)
- Canadian Occupational Performance Measure
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Fatigue Severity Scale (FSS)
- Fugl-Meyer Assessment (FMA)
- Functional Independence Measure (FIM)
- Goal Attainment Scaling (GAS) score
- Spinal Cord Independence Measure (SCIM)
| 9 months | 10 July 2023 | 01 August 2023 | 2 | |
| NCT05967325 | SVF Combined With Functional Self-assembling Peptide Nanofiber Hydrogels in the Treatment of Spinal Cord Injury | Kunming Tongren Hospital | | - Age 18 - 60 yrs
- Level T1-T12
AIS A- ≥ 3 months
- NOT have osteoporosis or had joint disease
- NOT have internal medical and/or infectious diseases
- have rating A on the American Spinal Injury Association (ASIA) measurement scale
- NOT have a history of multiple sclerosis or peripheral demyelination
- NOT have signs of kidney, cardiovascular, liver disorders
| | 15 | NA | Biological/cell based | Standing/walking/mobility | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Spinal Cord Independence Measure (SCIM)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 12 months | 15 July 2023 | 01 August 2023 | 1 | |
| NCT05960448 | Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury | James J. Peters Veterans Affairs Medical Center | | - Age ≥ 18 yrs
- Level C3-T6
AIS A, B, C- ≥ 1 years
- NOT have a history of seizures
- NOT have diabetes
| Recruiting | 20 | NA | Technology | General health | - Blood Pressure and Heart Rate Regulation
- Ratings of Perceived Exertion (RPE)
| 90 minutes | 30 July 2023 | 25 July 2023 | 2 | |
