Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 20 October 2023, updated 122 days ago

About this trial

This pilot trial is enrolling 2 individuals with chronic spinal cord injuries to test the feasibility of using non-invasive images of the spinal cord to define the best placement of an epidural spinal cord stimulator (ESCS) and the effect it has on voluntary movement. ESCS is a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord to modify spinal cord function. If included, participants will receive a surgically implanted epidural stimulator optimized for lower extremity and joint movement, and 6 months of intensive outpatient physical therapy. The goal is restoration of voluntary leg movement. Final testing of lower limb movement will be performed after 8 months.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C7 - T8
  • Severity (AIS)?
  • AIS-B
    Time since injury
    ≥ 6 months
    Healthy volunteers
    No
    C7-T8
    Additionally, participants must
    NOT be shorter than 5'1" or taller than 6'3"
    NOT have unstable cardiorespiratory issues

    What’s involved

    Type

    Technology

    Details

    - Participants will receive a surgically implanted epidural stimulator with the goal of restoring voluntary movement. - The intervention includes epidural stimulation and 6 months of intensive outpatient physical therapy. - Final testing of lower limb movement will be performed after 8 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Mental health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Dec 2023
    • Organisation
    • University of Colorado, Denver
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Dec 2023
    • Organisation
    • University of Colorado, Denver

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more