Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury

Technology
Standing/walking/mobility
Online since 1 September 2023, updated 20 days ago

About this trial

This proof-of-concept case series will prospectively use magnetic resonance imaging (MRI) evidence of spared spinal cord neural fibers to guide the selection of 2 research participants to receive a su...

Included participants

Gender
All
Age
≥ 18 years
Injury level
C7 - T8
  • Severity (AIS)?
  • AIS-B
    Time since injury
    ≥ 6 months
    Healthy volunteers
    No
    C7-T8

    What’s involved

    Type

    Technology

    Details

    This is an investigator-initiated proof of concept study performed at the University of Colorado Anschutz Medical Campus (CU Anschutz). This 2-case proof-of-concept study will include 2 research participants with motor-complete SCI to evaluate the performance of the Medtronic epidural stimulator for restoring voluntary movement below the level of injury. Participants will be enrolled at CU Anschutz. Screening data will be reviewed to determine participant eligibility. Two participants who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. The following treatment regimen will be used: epidural stimulation + 6 months of intensive outpatient physical therapy. Total duration of study participation will be 8 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Mental health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Dec 2023
    • Organisation
    • University of Colorado, Denver
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Dec 2023
    • Organisation
    • University of Colorado, Denver

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more