| NCT06700304 | CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices | Neuralink Corp | | - Age ≥ 19 yrs
- Level C1-T1
AIS B- ≥ 12 months
- NOT have an active implanted devices
- Not require an MRI during the study
| Recruiting | 6 | NA | Technology | General health | - Adverse Events (AEs)
- Generalized Anxiety Disorder (GAD-7)
- Patient Health Questionnaire-9 (PHQ-9)
| 6 years | 20 November 2024 | 21 November 2024 | 1 | |
| NCT07167680 | Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters | University of Illinois at Urbana-Champaign | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
| Recruiting soon | 120 | NA | Psychosocial/other | General health | - System Usability Scale (SUS)
- Wheelchair Skills Test (WST, 4.1)
| 14 weeks | 01 September 2025 | 11 September 2025 | 1 | |
| NCT06543277 | Safety and Feasibility of Paired Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Upper Limb Rehabilitation in Incomplete Spinal Cord Injury | The University of Texas Health Science Center, Houston | | - Age ≥ 18 yrs
- Level C1-C8
AIS B, C, D- 12 months - 10 years
- NOT have intracranial metal implants or pacemakers
| Recruiting | 12 | NA | Technology | General health | - Adverse Events (AEs)
- Blood Pressure and Heart Rate Regulation
- Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- Feasibility
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Patient Health Questionnaire-9 (PHQ-9)
- Spinal Cord Independence Measure (SCIM)
- Toronto Rehabilitation Institute Hand Function Test
| 20 weeks | 15 August 2025 | 07 August 2024 | 2 | |
| NCT07036107 | A Trial on the Clinical and Socioeconomic Impact of Wearable Exoskeletons for Spinal Cord Injury Rehabilitation in the Spanish Healthcare System | ABLE Human Motion S.L. | | - Age 18 - 70 yrs
- Level C5-L5
AIS A, B, C, D- ≤ 6 months
| Recruiting | 80 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 2 Minute Walk Test
- 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Blood Pressure and Heart Rate Regulation
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- Spinal Cord Assessment Tool for Spastic Reflexes (SCATS)
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 4 months | 15 January 2026 | 25 June 2025 | 2 | |
| NCT06708026 | Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults with SCI | The Hong Kong Polytechnic University | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 6 months
- BE ABLE to communicate in Cantonese
- NOT have contraindication for undergoing MRI
| Recruiting soon | 46 | NA | Psychosocial/other | Mental health and psychosocial factors | - Beck Depression Inventory (BDI)
- Brief Pain Inventory (BPI)
- Exercise Self-Efficacy Scale (ESES)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
| 3 months | 01 March 2025 | 27 November 2024 | 1 | |
| NCT06725836 | Clinical Testing of Invasive Spinal Cord Stimulation and Evaluation of Its Physiological Effects Using the Electroencephalography | Far Eastern Federal University | | - Age All ages
- Level C1-S5
AIS - All
- NOT have a history of epilepsy, stroke, or cancer
| Recruiting | 35 | NA | Surgery | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Neurogenic Bladder Symptom Score
- Short Form 36 (SF-36)
- Spinal Cord Independence Measure (SCIM)
| 2 weeks | 22 April 2023 | 10 December 2024 | 6 | |
