| NCT06891989 | Effects of a Mobile App-Based Mindfulness Intervention in Persons with Spinal Cord Injury and Chronic Pain | The University of Texas Health Science Center, Houston | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 6 months
| Recruiting soon | 282 | NA | Psychosocial/other | Pain | - Generalized Anxiety Disorder (GAD-7)
- Pain Numeric Rating Scale (NRS)
- Patient Health Questionnaire-9 (PHQ-9)
| 6 weeks | 01 January 2026 | 24 March 2025 | 1 | |
| NCT06841198 | Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury | Kessler Foundation | | - Age 18 - 75 yrs
- Level C1-T6
AIS A, B- 7 days - 50 days
- NOT have an implanted devices such as brain, spine, or nerve stimulators, a cardiac pacemaker, defibrillator, or intra-cardiac lines
| Recruiting | 5 | NA | Technology | General health | - Blood Pressure and Heart Rate Regulation
| 1 year | 01 April 2025 | 24 February 2025 | 1 | |
| NCT06840899 | CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury | University of Wisconsin, Madison | | - Age ≥ 18 yrs
- Level C1-L5
AIS - All
| Recruiting | 20 | PHASE2 | Drug | Bladder health/function | - Adverse Events (AEs)
- Neurogenic Bladder Symptom Score
| 4 months | 01 December 2025 | 21 February 2025 | 1 | |
| NCT06829212 | Research on Wireless Brain Implant System for General Control of External Devices | Shanghai StairMed Technology Co., Ltd. | | - Age 18 - 80 yrs
- Level C1-S5
AIS - ≥ 1 years
- NOT have previously implantated metal objects or devices (except dental implants or non-impacting implants)
| Recruiting | 4 | NA | Surgery | General health | | 7 months | 01 March 2025 | 17 February 2025 | 1 | |
| NCT06867809 | Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury | Columbia University | | - Age ≥ 18 yrs
- Level C4-T1
AIS B, C, D- ≥ 1 years
- NOT have a cardiac pacemaker/defibrillator
- NOT have ferromagnetic metallic implants in the head (except for within mouth)
- Not have implanted brain stimulators
- Not have intracranial aneurysm clips.
- Not have any active implanted device including intrathecal medication pumpos or existing spinal cord stimulators (does not include non-active spinal instrumentation such as rods, screws, or interbody devices).
- Not have Cochlear implants.
- Not have family history of ideiopathic epilepsy in a first degree relative.
- Not have any history of seizures.
| Recruiting | 20 | NA | Surgery | Arm/hand function | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Box and Block Test (BBT)
- Canadian Occupational Performance Measure
- Capabilities of Upper Extremity Instrument (CUE- Q and CUE-T)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Motor Evoked Potentials (MEPs)
| 30 weeks | 15 January 2026 | 10 March 2025 | 2 | |
| NCT06836739 | At-Home Genital Nerve Stimulation for SCI Bowel | MetroHealth Medical Center | | - Age ≥ 18 yrs
- Level C1-T12
AIS A, B, C, D- ≥ 6 months
- NOT have a cardiac pacemaker, implanted defibrillator, or other implanted functional electrical stimulation device if, upon clinical evaluation, it may have an interaction with the stimulation
| Recruiting | 12 | NA | Technology | Bowel health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Bowel and bladder control
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- SCI-QOL Bowel Management Difficulties
| 6 weeks | 01 March 2025 | 20 February 2025 | 1 | |
