Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury
About this trial
This trial is enrolling 6 participants with chronic incomplete spinal cord injury to test the effect of deep brain stimulation (DBS) on walking function. DBS is the stimulation of deeper parts of the brain through surgically implanted electrodes. In this study DBS targets an area of the brain called the cuneiform nucleus (CnF). If included, participants will undergo bilateral surgical implantation of DBS electrodes and participate in training sessions 3 times per week both before and after implantation. Final testing of walking function will be performed after 8 months.
Included participants
What’s involved
Type
Details
- Participants will undergo bilateral surgical implantation of deep brain stimulation (DBS) electrodes. - DBS is the stimulation of deeper parts of the brain through surgically implanted electrodes. - Additionally, participants will attend 60-minute training sessions 3 times per week, before and after DBS implantation, including stretching, active hip mobility, weight shifting, stepping, and walking practice. - Final testing of walking function will be performed after 8 months.
Potential benefits
Main benefits
Standing/walking/mobility
Additional benefits
General health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 30 Nov 2025
- Organisation
- University of Miami
- Trial recruitment status
- Recruiting
- Trial start date
- 30 Nov 2025
- Organisation
- University of Miami
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more