| NCT06437548 | Epidural Stimulation for Upper Extremity Function | Brigham and Women's Hospital | | - Age 18 - 65 yrs
- Level C1-T1
AIS - All
- NOT have a functional implanted device (pacemaker, vagus nerve device, baclofen pump)
- have had upper extremity nerve transfer > 6 months prior to enrollment
| Recruiting soon | 20 | NA | Technology | Arm/hand function | - Pain Numeric Rating Scale (NRS)
| 6 weeks | 01 September 2024 | 31 May 2024 | 0 | |
| NCT06393205 | Efficacy of Naso-Esophageal Tube Feeding in Patients With High Cervical Spinal Cord Injury. | Chao Phya Abhaibhubejhr Hospital | | - Age ≥ 18 yrs
- Level C1-C4
AIS - All
| Recruiting soon | 100 | NA | Technology | General health | | 15 days | 01 April 2024 | 01 May 2024 | 0 | |
| NCT06410001 | CE-STAND: Cervical Epidural STimulation After Neurologic Damage | University of Minnesota | | - Age ≥ 22 yrs
- Level C4-C7
AIS A, B- ≥ 1 years
| Recruiting soon | 36 | PHASE1, PHASE2 | Surgery | General health | - American Spinal Injury Association Impairment Scale (AIS)
- Blood Pressure and Heart Rate Regulation
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Surface Electromyography (sEMG)
| 1 year | 01 March 2026 | 10 May 2024 | 1 | |
| NCT06375759 | Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia | Xuanwu Hospital, Beijing | Parallel Assignment | - Age 18 - 80 yrs
- Level C1-S5
AIS - All
- Have a syringomyelia documented with MRI
| Recruiting | 200 | Not Applicable | Surgery | General health | - American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
| 2 years | 01 April 2024 | 19 April 2024 | 1 | |
| NCT06438991 | Spinal Cord Stimulation for Lower Extremity Function | Brigham and Women's Hospital | | - Age 18 - 65 yrs
- Level C6-T10
AIS B, C- ≥ 12 months
| Recruiting soon | 10 | NA | Technology | Standing/walking/mobility | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 6 months | 01 July 2024 | 03 June 2024 | 0 | |
| NCT06406855 | Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI) | University of Miami | | - Age 21 - 70 yrs
- Level C1-T10
AIS B, C, D- ≥ 6 months
- NOT have traumatic brain injury, stroke, multiple sclerosis, or other neuromuscular disorders that could affect neuromotor function and walking.
- NOT have metal implants in their head
- walk overground for at least 10 meters with some assistance of a therapist and minimal body-weight support
| Recruiting | 12 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Reintegration to Normal Living (RNL) Index
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 6 months | 07 May 2024 | 09 May 2024 | 1 | |
