Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

General health
Online since 10 December 2024, updated 99 days ago

About this trial

The proposed study seeks to understand how the cervical spinal cord should be stimulated after injury through short-term physiology experiments that will inform a preclinical efficacy trial. The purpo...

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - T1
  • Severity (AIS)?
  • Time since injury
    All
    Healthy volunteers
    No
    C1-T1
    Additionally, participants must
    NOT have stimulation devices in the neck or chest (e.g., vagal nerve stimulation, cardiac patients with pacemakers)

    What’s involved

    Type

    Observational

    Details

    For people with cervical spinal cord injury (SCI), regaining hand and arm function is their highest priority. Epidural stimulation enables recovery of walking and autonomic function in people with chronic SCI, but how the spinal cord should be stimulated to restore arm and hand function is not known. This project seeks to advance our understanding of how best to apply epidural electrical stimulation (EES) after cervical SCI using complementary experiments in humans and rats. This improved understanding will be used to conduct a preclinical study of the efficacy of different sites of cervical spinal cord stimulation.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 6 Dec 2024
    • Organisation
    • Columbia University
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 6 Dec 2024
    • Organisation
    • Columbia University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more