Activity-Based Therapy and Transcutaneous Spinal Cord Stimulation After Spinal Cord Injury (ABT-TCSCS)

Technology
Arm/hand function
Online since 22 November 2024, updated 13 days ago

About this trial

This trial is enrolling 24 individuals with chronic cervical spinal cord injury to test the feasibility and efficacy of activity-based therapy combined with transcutaneous spinal cord stimulation (SCS) on upper limb function. Activity-based therapy involves high intensity and effortful exercises of the individual receiving therapy. SCS is a technique for stimulating the spinal cord via skin surface electrodes to modify spinal cord function. If included, participants will undergo 12 sessions of activity-based therapy followed by 28 sessions of activity-based therapy combined with SCS. Final testing of arm and hand function will be performed after 11 weeks.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - C8
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 6 months
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C1-C8
    Additionally, participants must
    A score of greater than 2 out of 15 on the upper extremity motor scores

    What’s involved

    Type

    Technology

    Details

    - Participants will complete 12 sessions of activity-based therapy over 4 weeks, followed by 28 sessions combining activity-based therapy with transcutaneous spinal cord stimulation (SCS) over 7 weeks. - SCS is a technique for stimulating the spinal cord via surface stimulation to modify spinal cord function. - Activity-based therapy a form of therapy that is high intensity, more sessions, and effortful engagement from the individual receiving therapy. - Each session lasts 1 hour and is conducted three times per week. - Final testing of arm and hand function will be conducted at the end of the 11-week program.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Sensory function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 7 Oct 2022
    • Organisation
    • University Health Network, Toronto
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 7 Oct 2022
    • Organisation
    • University Health Network, Toronto

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more