| NCT06406855 | Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI) | University of Miami | | - Age 21 - 70 yrs
- Level C1-T10
AIS B, C, D- ≥ 6 months
- NOT have traumatic brain injury, stroke, multiple sclerosis, or other neuromuscular disorders that could affect neuromotor function and walking.
- NOT have metal implants in their head
- walk overground for at least 10 meters with some assistance of a therapist and minimal body-weight support
| Recruiting | 12 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Berg Balance Scale (BBS)
- Reintegration to Normal Living (RNL) Index
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 6 months | 07 May 2024 | 09 May 2024 | 1 | |
| NCT06351852 | Transdermal Administration by a Novel Wireless Iontophoresis Device | James J. Peters Veterans Affairs Medical Center | | - Age 18 - 89 yrs
- Level C1-S5
AIS - All
- NOT have a deep brain stimulation device
- NOT have a history of bowel or bladder obstruction
- NOT have a history of heart conditions including coronary artery disease, myocardial infarctions, or arrhythmias
| Ended | 2 | EARLY_PHASE1 | Drug | Bowel health | - Bristol Stool Form Scale (BSFS)
| 3 days | 22 March 2022 | 08 April 2024 | 2 | |
| NCT05492188 | Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI | Medical University of South Carolina | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 1 years
- have neuropathic pain in lower leg
- NOT have peripheral neuropathy
- NOT have motoneuron injury
| Recruiting | 15 | NA | Technology | Pain | - Functional Independence Measure (FIM)
- Neuropathoc Pain Symptom Inventory (NPSI)
- Quantitative Sensory Testing (QST)
- Spinal Cord Independence Measure (SCIM)
| 3 months | 27 March 2023 | 08 August 2022 | 1 | |
| NCT06214546 | Effect of Different Support Systems on Gait | Sint Maartenskliniek | | - Age ≥ 18 yrs
- Level C1-S5
AIS C, D- ≥ 2 weeks
- be between 150 and 195 cm tall
- NOT have an oncological spinal cord injury
- NOT have a stoma
| Ended | 15 | NA | Rehabilitation | Standing/walking/mobility | | 1 day | 25 October 2023 | 19 January 2024 | 1 | |
| NCT06347575 | Safety and Tolerability of a Novel Implantable Neurostimulator for Ameliorate Erectile Function on Spinal Cord Injured Patients | Assistance Publique - Hôpitaux de Paris | | - Age 18 - 45 yrs
- Level T7-L5
AIS - ≥ 6 months
- have a monogamous relationship with a female sexual partner
- NOT have history of priapism or Lapeyronie's disease
- History of erectile dysfunction
- History of insufficient reposonse to PDE5 Inhibitor Drug ie. slidenafil
| Ended | 0 | NA | Surgery | Sexual health | - Pain Visual Analog Scale (VAS)
| 6 months | 01 May 2024 | 04 April 2024 | 2 | |
| NCT06438471 | Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury | EicOsis Human Health Inc. | | - Age ≥ 18 yrs
- Level C2-T12
AIS - ≥ 12 months
- NOT have other chronic neuropathic pain conditions, including painful diabetic neuropathy, HIV-associated neuropathic pain, chemotherapy or ethanol-associated neuropathy.
- be United States veterans
| Recruiting | 36 | PHASE1 | Drug | General health | - Adverse Events (AEs)
- Neuropathoc Pain Symptom Inventory (NPSI)
| 30 days | 15 April 2025 | 03 June 2024 | 1 | |
