| NCT04755699 | Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis | Northwell Health | | - Age 18 - 75 yrs
- Level C1-C8
AIS A, B, C, D- 1 years - 75 years
- Have limited or no ability to use at least one hand.
- NOT have implanted medical devices (e.g. deep brain stimulator, epidural stimulator, cardiac pacemaker)
- NOT have a history of epilepsy.
- NOT have a history of serious mood disorder.
| Recruiting | 28 | EARLY_PHASE1 | Rehabilitation | Arm/hand function | | 12 months | 02 December 2020 | 16 February 2021 | 1 | |
| NCT05527691 | Testing SupportGroove: a Novel Mhealth Intervention for Couples Coping with Spinal Cord Injury | University of Utah | | - Age ≥ 18 yrs
- Level -
AIS - 3 months - 5 years
| Ended | 168 | NA | Psychosocial/other | Mental health and psychosocial factors | - Patient Health Questionnaire-9 (PHQ-9)
| 28 weeks | 03 October 2022 | 02 September 2022 | 2 | |
| NCT05398913 | Effects of Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury | Hospital Nacional de Parapléjicos de Toledo | | - Age 18 - 65 yrs
- Level C4-L1
AIS D- ≥ 1 years
- Have an assessable level of walking ability (with or without walking aid)
| Ended | 8 | PHASE1, PHASE2 | Drug | Standing/walking/mobility | - 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Beck Depression Inventory (BDI)
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Fatigue Severity Scale (FSS)
- Hospital Anxiety and Depression Scale (HADS)
- Penn Spasm Frequency Scale (PSFS)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 15 days | 12 May 2021 | 01 June 2022 | 1 | |
| NCT05422716 | "Epidural Spinal Cord Stimulation: Addressing Spasticity and Motor Function" | Kessler Foundation | Parallel Assignment | - Age ≥ 18 yrs
- Level -
AIS - All
- meet the clinical criteria for an intrathecal baclofen pump
| Recruiting soon | 20 | Not Applicable | Technology | Spasticity | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Electromyography
- Neuromuscular Recovery Scale
- Penn Spasm Frequency Scale (PSFS)
| 8 months | 14 July 2022 | 16 June 2022 | 0 | |
| NCT05369520 | Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury | University of British Columbia | | - Age 18 - 60 yrs
- Level C1-T6
AIS A, B- ≥ 1 years
- Be a resident of British Columbia, Canada with active provincial medical services plan
- NOT be ventilator dependent
- NOT have history of cardiovascular, respiratory, bladder, or renal disease unrelated to SCI
- NOT have history of seizures(epilepsy or recurring headaches
- NOT have an intrathecal baclofen pump
- NOT have had past electrode implantation surgery
- NOT have implanted metal in the skull or pacemakers, stimulators, or medication pumps in the trunk
- NOT have history of gastrointestinal atresia or stenosis
| Recruiting | 30 | NA | Technology | General health | - Incontinence Quality of Life Questionnaire (I-QOL)
- Neurogenic Bladder Symptom Score
- Short Form 36 (SF-36)
- Surface Electromyography (sEMG)
| 8 weeks | 03 October 2023 | 11 May 2022 | 2 | |
| NCT05084170 | Cingulotomy for Refractory Neuropathic Pain Following Spinal Cord Injury (CRNP-SCI) | St George's, University of London | | - Age 18 - 70 yrs
- Level -
AIS - ≥ 12 months
| | 12 | | Surgery | Pain | | | 01 May 2021 | 19 October 2021 | 1 | |
