Effects of Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury

Drug
Standing/walking/mobility
Online since 11 November 2022, updated 588 days ago

About this trial

This phase 1/phase 2 trial is enrolling individuals with incomplete chronic cervical and thoracic spinal cord injuries to test the effect of a drug (Rimonabant) on walking ability. If included, participants will either take: 1) two pills of placebo; 2) one pill of placebo and one pill of Rimonabant (2.5mg); or 3) two pills of Rimonabant (5mg) once per day for 5 consecutive days. Final testing will be performed after 15 days.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C4 - L1
  • Severity (AIS)?
  • AIS-D
    Time since injury
    ≥ 1 year
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C4-L1
    Additionally, participants must
    Have an assessable level of walking ability (with or without walking aid)

    What’s involved

    Type

    Drug

    Details

    Participants will receive either 1) two pills of placebo, 2) one pill of placebo and one pill of Rimonabant (2.5mg) or 3) two pills of Rimonabant once per day on 5 consecutive days.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Mental health and psychosocial factors

    Pain

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Ended
    • Trial start date
    • 12 May 2021
    • Organisation
    • Hospital Nacional de Parapléjicos de Toledo
    • Trial recruitment status
    • Ended
    • Trial start date
    • 12 May 2021
    • Organisation
    • Hospital Nacional de Parapléjicos de Toledo

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more