| NCT05970367 | Intensive Motor Rehabilitation With Technology for Patients With Central Neurological Disease | KU Leuven | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- ≥ 3 months
- be able to initiate movements against gravity
- NOT have severe visual impairment, communication, cognitive and language formation problems
- be at least 3 months post discharge from hospital/rehabilitation center, living at home
| Active | 102 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Action Research Arm Test (ARAT)
- Canadian Occupational Performance Measure
- European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L)
- Fatigue Severity Scale (FSS)
- Fugl-Meyer Assessment (FMA)
- Functional Independence Measure (FIM)
- Goal Attainment Scaling (GAS) score
- Spinal Cord Independence Measure (SCIM)
| 9 months | 10 July 2023 | 01 August 2023 | 2 | |
| NCT05967325 | SVF Combined With Functional Self-assembling Peptide Nanofiber Hydrogels in the Treatment of Spinal Cord Injury | Kunming Tongren Hospital | | - Age 18 - 60 yrs
- Level T1-T12
AIS A- ≥ 3 months
- NOT have osteoporosis or had joint disease
- NOT have internal medical and/or infectious diseases
- have rating A on the American Spinal Injury Association (ASIA) measurement scale
- NOT have a history of multiple sclerosis or peripheral demyelination
- NOT have signs of kidney, cardiovascular, liver disorders
| | 15 | NA | Biological/cell based | Standing/walking/mobility | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Spinal Cord Independence Measure (SCIM)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 12 months | 15 July 2023 | 01 August 2023 | 1 | |
| NCT05960448 | Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury | James J. Peters Veterans Affairs Medical Center | | - Age ≥ 18 yrs
- Level C3-T6
AIS A, B, C- ≥ 1 years
- NOT have a history of seizures
- NOT have diabetes
| Recruiting | 20 | NA | Technology | General health | - Blood Pressure and Heart Rate Regulation
- Ratings of Perceived Exertion (RPE)
| 90 minutes | 30 July 2023 | 25 July 2023 | 2 | |
| NCT05863988 | FES and Upper Limb Loading Exercises Outcome Comparison on Hand Function in Spinal Cord Injury Patients | Riphah International University | | - Age 20 - 50 yrs
- Level C5-T1
AIS B, C, D- All
- NOT have sustained autonomic dysreflexia due to stimulation
- NOT be taking long-term steriods
- NOT have pre-existing arm or hand injury
- NOT be taking cardioactive medications
- NOT have tendon transfers or implanted devices
- NOT have bleeding disorders
| | 30 | NA | Technology | Arm/hand function | - Action Research Arm Test (ARAT)
- Hand-Held Myometery / Dynamometry
| 8 weeks | 25 February 2023 | 18 May 2023 | 2 | |
| NCT04243044 | Influence of Transcutaneous Spinal Stimulation Intensity on Spasticity After SCI | Shepherd Center, Atlanta GA | | - Age ≥ 16 yrs
- Level C1-T12
AIS A, B, C, D- ≥ 3 months
- HAVE at least mild spasticity affecting the legs
- NOT have progressive spinal lesions
- NOT have cardiovascular irregularities
- NOT have cancer or a history of cancer
- NOT have orthopaedic problems that limit full leg range of motion
- NOT have used botox or selective dorsal rhizotomy
- NOT have implanted stimulator of any type
| Ended | 21 | NA | Technology | Spasticity | - Pendulum Test (Wartenberg)
- Penn Spasm Frequency Scale (PSFS)
| 2 weeks | 08 April 2022 | 27 January 2020 | 1 | |
| NCT05784285 | Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities | McGill University | | - Age 12 - 18 yrs
- Level C1-S5
AIS - All
- live in the provinces of Quebec or Ontario
- HAVE restricted mobility
| Recruiting soon | 150 | NA | Psychosocial/other | Mental health and psychosocial factors | - Canadian Occupational Performance Measure
- Hand-Held Myometery / Dynamometry
| 22 weeks | 01 November 2023 | 24 March 2023 | 1 | |