| NCT06099340 | Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure of Patients With Central Nervous System Injuries. | Nantes University Hospital | | - Age 18 - 80 yrs
- Level C1-S5
AIS C, D- ≤ 6 months
| Recruiting soon | 90 | NA | Rehabilitation | Standing/walking/mobility | | 10 weeks | 01 September 2024 | 25 October 2023 | 1 | |
| NCT05801536 | TCES for Upper Limb Function in Cervical SCI | University of Leeds | | - Age 18 - 80 yrs
- Level C3-C7
AIS - ≥ 1 years
- have difficulty with hand functions in activities of daily living (e.g. dressing, grooming, feeding)
- NOT use ventilator
- NOT have implanted stimulator (e.g. pacemaker)
| Ended | 5 | NA | Technology | Arm/hand function | - Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Motor evoked potential
- Spinal Cord Independence Measure (SCIM)
- Surface Electromyography (sEMG)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 17 months | 13 June 2022 | 06 April 2023 | 1 | |
| NCT05926596 | Leg Stretching Using an Exoskeleton on Demand for People With Spasticity | VA Office of Research and Development | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 6 months
- NOT have any other neurological disorders
- have spasticity
| Recruiting soon | 10 | NA | Rehabilitation | Standing/walking/mobility | | 24 weeks | 29 December 2025 | 03 July 2023 | 1 | |
| NCT05708274 | Pharmacological Agents for Chronic Spinal Cord Injury (SCI) | Bronx VA Medical Center | | - Age 18 - 65 yrs
- Level C1-C8
AIS - ≥ 12 months
- NOT have history of moderate to severe head trauma
- NOT have other neurological injury
- NOT have implanted stimulator, pacemaker, etc.
- have motor incomplete injury
- be able to perform thunb-index pinch
| Ended | 25 | PHASE1 | Drug | Arm/hand function | - Blood Pressure and Heart Rate Regulation
- Box and Block Test (BBT)
- Hand-Held Myometery / Dynamometry
- Nine Hole Peg Test
| 10 min after intervention | 20 January 2023 | 01 February 2023 | 2 | |
| NCT05968352 | Restoration of Bladder Function in Spinal Cord Injury | University of Oxford | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B- All
- have undergone implantation of a Finetech Brindley Bladder controller, with or without sacral posterior rhizotomy
- NOT have undergone external urethral sphincterotomy
| Ended | 0 | | Technology | Bladder health/function | | 3 hours | 18 November 2021 | 01 August 2023 | 1 | |
| NCT05966896 | Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury | University of Colorado, Denver | | - Age ≥ 18 yrs
- Level C7-T8
AIS B- ≥ 6 months
- NOT be shorter than 5'1" or taller than 6'3"
- NOT have unstable cardiorespiratory issues
| Recruiting soon | 2 | NA | Technology | Standing/walking/mobility | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 8 months | 01 August 2025 | 01 August 2023 | 0 | |
