| NCT04748835 | The SEEA (SCI Energy Expenditure and Activity) Study | Baylor Research Institute | | - Age ≥ 18 yrs
- Level C1-S5
AIS A, B, C, D- ≤ 18 months
| | 42 | | | General health | | | 20 September 2018 | 10 February 2021 | 1 | |
| NCT03592173 | Non-Invasive Stimulation for Improving Motor Function | Burke Medical Research Institute | | - Age 18 - 80 yrs
- Level C1-S5
AIS C, D- 6 months - 80 years
- have had a traumatic SCI for at least 6 months.
- have a neurological level of injury between C1-S5.
- have one of the following ASIA impairment scale (AIS):
- AIS C: incomplete; at least some feeling and mostly weak movement below the injury.
- AIS D: incomplete; at least some feeling and, some weak but mostly stronger movement below the injury).
- have some degree of motor function in ankle flexors and extensors.
- be between the ages of 18 and 80 years.
- NOT have another device implanted inside their body
- NOT have metal in any part of the body, including the eye.
- NOT have a history of epilepsy in the family.
- NOT have a history of seizures.
| Active | 30 | PHASE2 | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- Spinal Cord Independence Measure (SCIM)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| | 01 July 2013 | 19 July 2018 | 1 | |
| NCT03899584 | High Doses of 4-aminopyridine in Clinically Complete Chronic Spinal Cord Injury Patients. | Coordinación de Investigación en Salud, Mexico | | - Age 18 - 60 yrs
- Level C4-T12
AIS A- 2 years - 60 years
- have a spinal cord injury for at least 2 years.
- have a neurological level of injury between C4 and T12.
- have an ASIA impairment scale of AIS A: complete; no feeling or movement below the injury.
- be between the ages of 18 and 60 years.
- be able to breathe independently.
- have intact range of movement in the affected joints.
- NOT have a known allergy to pyridine-containing drugs.
| | 150 | PHASE3 | Drug | General health | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Short Form 36 (SF-36)
- Spinal Cord Independence Measure (SCIM)
| | 17 July 2019 | 02 April 2019 | 1 | |
| NCT04047992 | Seated Balance Using the Indego™ | James J. Peters Veterans Affairs Medical Center | | - Age ≥ 18 yrs
- Level T4-S5
AIS A, B, C, D- ≥ 6 months
- have a spinal cord injury for at least 6 months.
- have a neurological level of injury below T3.
- have one of the following ASIA impairment scale (AIS):
- AIS A: complete; no feeling or movement below the injury
- AIS B: incomplete; have some feeling, but no movement, below the injury
- AIS C: incomplete; at least some feeling and mostly weak movement below the injury
- AIS D: incomplete; at least some feeling and, some weak but mostly stronger movement below the injury)
- be a wheelchair user for indoor and outdoor mobility.
- be able to hold crutches in hands.
- be at least 18 years old.
- NOT be able to walk independently.
- NOT have a history of implanted brain/spine/nerve simulators, aneurysm clips, ferromagnetic metallic implants, or cardiac pacemaker/defibrillator.
| Recruiting | 20 | NA | Rehabilitation | Standing/walking/mobility | | | 01 February 2018 | 07 August 2019 | 2 | |
| NCT01353599 | Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury | James J. Peters Veterans Affairs Medical Center | | - Age 18 - 65 yrs
- Level C3-C8
AIS A, B, C, D- 1 years - 65 years
| | 50 | PHASE1 | Drug | General health | | | 01 August 2011 | 13 May 2011 | 3 | |
| NCT01516385 | Detection of Peripheral Blood Biomarkers in Intermediate Phase Spinal Cord Injury: Correlation With Neurological and Functional Outcomes, and Comparison to Other Central and Peripheral Neurological Conditions. | Sheba Medical Center | | - Age 18 - 75 yrs
- Level C1-S5
AIS A, B, C, D- 2 weeks - 3 months
| | 150 | | | General health | | | 01 January 2012 | 24 January 2012 | 1 | |
