| NCT06154122 | Virtual Reality Upper Limb Therapy for People With Spinal Cord Injury | Glasgow Caledonian University | | - Age ≥ 18 yrs
- Level C4-C8
AIS - All
- MUST be in-patients at the Queen Elizabeth National Spinal Injuries Unit in Glasgow
| Ended | 12 | NA | Rehabilitation | Arm/hand function | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Feasibility
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Pain Visual Analog Scale (VAS)
- Spinal Cord Independence Measure (SCIM)
| 12 weeks | 15 March 2024 | 01 December 2023 | 1 | |
| NCT06130449 | Testosterone and Neural Function | VA Office of Research and Development | | - Age 18 - 80 yrs
- Level C1-S5
AIS A, B, C, D- ≥ 12 months
- NOT have ventilator dependence or patent tracheostomy site
- NOT have implanted devices with electromagnetic properties
- NOT have a hitsory of other neurologic disorders or head trauma
- NOT have brain injury, stroke, tumor, multiple sclerosis, or abscess
| Recruiting | 15 | EARLY_PHASE1 | Drug | General health | - Blood Pressure and Heart Rate Regulation
- Electromyography
| 1 day | 01 April 2024 | 14 November 2023 | 2 | |
| NCT01621113 | Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury | Kessler Foundation | | - Age 18 - 70 yrs
- Level -
AIS - All
| Ended | 27 | PHASE2 | | | | | 01 June 2012 | 18 June 2012 | 1 | |
| NCT04631471 | Regeneration in Cervical Degenerative Myelopathy | Cambridge University Hospitals NHS Foundation Trust | Parallel Assignment | - Age 18 - 80 yrs
- Level C1-S5
AIS A, B, C, D- ≤ 80 years
- have a cervical degenerative myelopathy (spinal cord compression with neurological impairment because of degenerative disease of the cervical spine)
- have a preoperative modified Japanese Orthopedic Association (mJOA) score ≥8 and ≤14 (consistent with moderate to severe neurological impairment)
- not have had previous surgical decompression of the cervical spine
| Recruiting | 400 | Phase 3 | Surgery | Arm/hand function | | | 22 December 2021 | 17 November 2020 | 1 | |
| NCT05638191 | Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury | University of British Columbia | | - Age 18 - 70 yrs
- Level C5-C8
AIS A, B- 6 months - 9 months
| Recruiting | 60 | | Surgery | Arm/hand function | - Ashworth and Modified Ashworth Scale (MAS)
- Beck Depression Inventory (BDI)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Spinal Cord Independence Measure (SCIM)
| 2 years | 03 June 2021 | 06 December 2022 | 4 | |
| NCT04276181 | Combined Nerve and Tendon Transfer for the Restoration of Hand Function in Individuals With Tetraplegia | Göteborg University | | - Age 15 - 55 yrs
- Level C5-C7
AIS A, B, C, D- ≤ 12 months
- meet criteria for nerve transfer surgery
| Recruiting | 94 | | Surgery | Arm/hand function | | | 26 January 2020 | 19 February 2020 | 1 | |
