Functional Neural Regeneration Collagen Scaffold Transplantation in Acute Spinal Cord Injury Patients

Surgery
General health
Online since 18 March 2024, updated 119 days ago

About this trial

This Phase 1 trial is enrolling individuals with spinal cord injuries assessed to be complete (AIS A) within 21 days, to test the safety and efficacy of functional neural regeneration collagen scaffold transplantation. This is a procedure in which a scaffold made of collagen is implanted into the injured spinal cord. If included, participants will undergo surgery for transplantation of the scaffold followed by comprehensive rehabilitation and psychological assessment. Final testing of safety and neurological function will be performed after 12 months.

Included participants

Gender
All
Age
18 - 65 years
Injury level
C4 - T12
  • Severity (AIS)?
  • AIS-A
    Time since injury
    ≤ 21 days
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    C4-T12

    What’s involved

    Type

    Surgery

    Details

    - participants will undergo surgery for transplantation of the scaffold. - Final testing of safety and neurological function will be performed after 12 months.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Sensory function

    Standing/walking/mobility

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 Apr 2015
    • Organisation
    • Chinese Academy of Sciences
    • Trial recruitment status
    • Unknown
    • Trial start date
    • 1 Apr 2015
    • Organisation
    • Chinese Academy of Sciences

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more