NeuroRegen Scaffold™ With Bone Marrow Mononuclear Cells Transplantation vs. Intradural Decompression and Adhesiolysis in SCI
About this trial
This trial is enrolling 22 individuals with chronic thoracic spinal cord injuries to test the safety and efficacy of an implanted scaffold combined with stem cells (Bone Marrow Mononuclear Cells; BMMC) into the injured spinal cord compared to surgical decompression, on neurological recovery. The scaffold (NeuroRegen™) is a man-made structure intended to mimic the natural tissue environment to support stem cell growth. If included, participants will be randomly assigned to receive either 1) the scaffold with stem cells derived from bone marrow or 2) decompression surgery. After surgery, all participants will receive rehabilitation, psychological and nutritional care. Final testing of neurological function will be performed after 24 months. *Note: detailed information about the stem cells, source of cells, need for immune suppression, etc. is not available on clinicaltrials.gov and will need to be provided by the investigator.
Included participants
Traumatic
What’s involved
Type
Details
- participants will be randomly assigned to receive either 1) the scaffold with stem cell derived from bone marrow or 2) decompression surgery. - - The scaffold (NeuroRegen™) is a man-made structure intended to mimic the natural tissue environment to support stem cell growth. - After surgery, all participants will receive rehabilitation, psychological and nutritional care. - Final testing of neurological function will be performed after 24 months.
Potential benefits
Main benefits
General health
Additional benefits
Arm/hand function
Bladder health/function
Standing/walking/mobility
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Unknown
- Trial start date
- 1 Jan 2016
- Organisation
- Chinese Academy of Sciences
- Trial recruitment status
- Unknown
- Trial start date
- 1 Jan 2016
- Organisation
- Chinese Academy of Sciences
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more