NeuroRegen Scaffold™ With Bone Marrow Mononuclear Cells Transplantation vs. Intradural Decompression and Adhesiolysis in SCI

About this trial

This trial is enrolling 22 individuals with chronic thoracic spinal cord injuries to test the safety and efficacy of an implanted scaffold combined with stem cells (Bone Marrow Mononuclear Cells; BMMC) into the injured spinal cord compared to surgical decompression, on neurological recovery. The scaffold (NeuroRegen™) is a man-made structure intended to mimic the natural tissue environment to support stem cell growth. If included, participants will be randomly assigned to receive either 1) the scaffold with stem cells derived from bone marrow or 2) decompression surgery. After surgery, all participants will receive rehabilitation, psychological and nutritional care. Final testing of neurological function will be performed after 24 months. *Note: detailed information about the stem cells, source of cells, need for immune suppression, etc. is not available on clinicaltrials.gov and will need to be provided by the investigator.