| NCT02274116 | Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury | Spaulding Rehabilitation Hospital | | - Age 18 - 75 yrs
- Level C2-L5
AIS - ≥ 6 months
| Active | 30 | NA | Drug | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
| 4 weeks | 01 October 2014 | 24 October 2014 | 1 | |
| NCT02232165 | Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury | University of Calgary | | - Age ≥ 16 yrs
- Level C1-T12
AIS A, B, C- ≤ 24 hours
| Ended | 17 | NA | Drug | Arm/hand function | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Functional Independence Measure (FIM)
- Short Form 36 (SF-36)
- Spinal Cord Independence Measure (SCIM)
| 1 year | 01 February 2013 | 05 September 2014 | 2 | |
| NCT02031835 | Body Weight Supported Treadmill Training as Physical Therapy Treatment to Spinal Cord Injury Patients | University of Ioannina | | - Age 8 - 88 yrs
- Level C5-T12
AIS B, C, D- All
| Ended | 26 | NA | Rehabilitation | Standing/walking/mobility | - American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Ashworth and Modified Ashworth Scale (MAS)
- Barthel Index (BI)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 6 weeks | 01 March 2012 | 09 January 2014 | 1 | |
| NCT01923662 | A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes | VA Office of Research and Development | | - Age ≥ 21 yrs
- Level C6-T12
AIS A, B, C, D- ≥ 6 months
- be capable of moving hip, knee and ankle joints through normal range of motion
| Ended | 6 | NA | Technology | Standing/walking/mobility | | 12 months | 11 April 2013 | 15 August 2013 | 1 | |
| NCT01772810 | Safety Study of Human Spinal Cord-derived Neural Stem Cell Transplantation for the Treatment of Chronic SCI | Neuralstem Inc. | | - Age 18 - 65 yrs
- Level C5-C7
AIS A- 1 years - 2 years
- live within 500 miles from University of California San Diego Medical Center
- NOT have penetrating injury, e.g. gunshot or knife wound
- NOT have received investigational drug or device within 30 days of stem cell operation
- NOT have implanted spine stimulator
| | 8 | PHASE1 | Biological/cell based | Standing/walking/mobility | - Adverse Events (AEs)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
| 60 months | 01 August 2014 | 21 January 2013 | 1 | |
| NCT01714349 | Nerve Transfer After Spinal Cord Injuries | Washington University School of Medicine | | - Age 18 - 65 yrs
- Level C1-C8
AIS A, B, C- 6 months - 48 months
- have no significant pain
- show minimal or no evidence of motor function improvement after 6 months post-injury
| Ended | 20 | NA | Surgery | Arm/hand function | | 48 months | 01 October 2012 | 25 October 2012 | 2 | |
