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NCTID
Brief title
Sponsor
Design
Criteria
Status
Target enrollment
Study phase & design
Primary intervention type
Primary potential benefit
Outcome measure
Follow up
Start date
First posted
Location
NCT07254767Virtual Walking and Neuromulation to Reduce Neuropathic Pain After a Spinal Cord InjuryCentre for Interdisciplinary Research in Rehabilitation of Greater Montreal
  • Age ≥ 18 yrs
  • Level C1-S5
  • AIS A, B, C, D
  • All
  • NOT have a pacemaker or metallic implants in the brain or eyes
Recruiting soon10NATechnologyPain
  • Feasibility
  • Numeric Pain Rating Scale
8 months01 December 202528 November 20250
NCT07223710Improving Walking After Spinal Cord InjuryShirley Ryan AbilityLab
  • Age 18 - 75 yrs
  • Level C1-T10
  • AIS C, D
  • ≥ 6 months
  • NOT have metal implants in the head
Recruiting soon20PHASE1, PHASE2TechnologyStanding/walking/mobility
  • 10 Meter Walking Test (10 MWT)
  • Ashworth and Modified Ashworth Scale (MAS)
  • Motor Evoked Potentials (MEPs)
12 days15 November 202503 November 20251
NCT07253233Treatment of Spinal Cord Injury Using Autologous Concentrated Growth FactorsThird Affiliated Hospital, Sun Yat-Sen University
  • Age 18 - 60 yrs
  • Level C1-S5
  • AIS C, D
  • All
Recruiting soon10EARLY_PHASE1DrugGeneral health
  • 10 Meter Walking Test (10 MWT)
  • American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
  • Ashworth and Modified Ashworth Scale (MAS)
  • Hospital Anxiety and Depression Scale (HADS)
  • Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
  • Neurogenic Bowel Dysfunction Score (NBD or NBDS)
  • Penn Spasm Frequency Scale (PSFS)
  • Sensory evoked potentials (including mixed and dermatomal, mSSEPs, dSSEPs, contact heat/laser evoked potentials- CHEPS/LEPs)
  • Spinal Cord Independence Measure (SCIM)
12 months01 December 202528 November 20250
NCT07295067Extracellular Vesicles for the Treatment of SyringomyeliaXuanwu Hospital, Beijing
  • Age 18 - 60 yrs
  • Level C1-S5
  • AIS
  • All
Recruiting18PHASE1Biological/cell basedGeneral health
  • Adverse Events (AEs)
  • American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
1 year23 December 202519 December 20251
NCT07303582Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower ExtremitiesOxford University Hospitals NHS Trust
  • Age ≥ 18 yrs
  • Level C1-S5
  • AIS
  • All
Recruiting50PHASE4DrugPain
  • Ashworth and Modified Ashworth Scale (MAS)
  • Barthel Index (BI)
  • Goal Attainment Scaling (GAS) score
  • Neuropathoc Pain Symptom Inventory (NPSI)
24 weeks02 December 202526 December 20251
NCT07306052Epidural Spinal Cord Stimulation for Restoring Walking in Spinal Cord InjurySecond Affiliated Hospital, School of Medicine, Zhejiang University
  • Age 16 - 65 yrs
  • Level C1-T9
  • AIS C, D
  • 6 months - 3 years
  • NOT have an implanted cardiac pacemakers, cardioverters, or defibrillators
Recruiting12NATechnologyStanding/walking/mobility
  • 10 Meter Walking Test (10 MWT)
  • 6-Minute Walk Test (6MWT)
  • Adverse Events (AEs)
  • American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
  • Ashworth and Modified Ashworth Scale (MAS)
  • Functional Independence Measure (FIM)
  • Pain Visual Analog Scale (VAS)
  • Penn Spasm Frequency Scale (PSFS)
  • Spinal Cord Independence Measure (SCIM)
  • Walking Index for Spinal Cord Injury (WISCI) and WISCI II
12 December 202529 December 20251