| NCT07289191 | Development of a Novel Strategy to Analyze the Effect on Gait Using Transcutaneous Spinal Current Stimulation in Incomplete Spinal Cord Injured Patients | Institut Guttmann | | - Age 18 - 75 yrs
- Level C1-S5
AIS D- ≥ 6 months
| Recruiting | 10 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- American Spinal Injury Association Impairment Scale (AIS)
- Ashworth and Modified Ashworth Scale (MAS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Motor Evoked Potentials (MEPs)
- Surface Electromyography (sEMG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 4 weeks | 01 January 2021 | 17 December 2025 | 1 | |
| NCT07280351 | Duraplasty for Acute Traumatic Spinal Cord Injury | University of California, San Francisco | | - Age 18 - 80 yrs
- Level C3-C7
AIS A, B, C- ≤ 24 null
| Recruiting soon | 66 | NA | Surgery | General health | - American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Magnetic Resonance Imaging (MRI) - conventional/anatomical and quantitative
- Short Form 36 (SF-36)
- Spinal Cord Independence Measure (SCIM)
| 6 months | 01 March 2026 | 12 December 2025 | 1 | |
| NCT07308808 | Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation | Medstar Health Research Institute | | - Age ≥ 18 yrs
- Level C1-S5
AIS - ≥ 6 months
- use intermittent catheterization for bladder management
| Recruiting | 40 | EARLY_PHASE1 | | Bladder health/function | | 23 days | 09 September 2025 | 30 December 2025 | 1 | |
| NCT07224256 | VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration | Neuralink Corp | | - Age 22 - 75 yrs
- Level C1-T1
AIS - All
| Recruiting | 6 | NA | Technology | General health | | 2 years | 03 October 2025 | 04 November 2025 | 1 | |
| NCT07272967 | Metformin in Preventing Secondary Gliosis Following Acute Thoraco-Lumbar Spinal Cord Injury | Badr University | | - Age 18 - 65 yrs
- Level T1-L2
AIS B, C, D- ≤ 24 null
- NOT have implanted metallic devices or conditions precluding MRI
| Recruiting soon | 34 | PHASE4 | Drug | General health | - American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Neuropathoc Pain Symptom Inventory (NPSI)
- Pain Visual Analog Scale (VAS)
| 3 months | 01 January 2026 | 09 December 2025 | 1 | |
| NCT07295067 | Extracellular Vesicles for the Treatment of Syringomyelia | Xuanwu Hospital, Beijing | | - Age 18 - 60 yrs
- Level C1-S5
AIS - All
| Recruiting | 18 | PHASE1 | Biological/cell based | General health | - Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
| 1 year | 23 December 2025 | 19 December 2025 | 1 | |