| NCT06248476 | Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | | - Age 18 - 45 yrs
- Level C1-S5
AIS C, D- ≥ 12 months
- NOT have epileptic seizures
- NOT have a metalic implant in brain or scalp
- NOT have a pacemaker
- Be able to walk at least 10 meters independently or with canadian, walker or walking stick
| Ended | 30 | NA | Technology | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Motor Evoked Potentials (MEPs)
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 6 weeks | 01 March 2023 | 08 February 2024 | 2 | |
| NCT06672458 | Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI) | University of Miami | | - Age 18 - 70 yrs
- Level C1-T1
AIS A, B, C, D- All
- NOT have an implanted neurostimulator, e.g., deep brain stimulation (DBS), epidural/subdural, vagal nerve stimulation (VNS)
- NOT have a cardiac pacemaker or intracardiac lines
| Recruiting | 60 | NA | Technology | Arm/hand function | - Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Manual Muscle Test (MMT)
- Nine Hole Peg Test
- Surface Electromyography (sEMG)
| 12 weeks | 01 November 2024 | 04 November 2024 | 1 | |
| NCT06611748 | Restoration of Hand Function in Cervical SCI | MetroHealth Medical Center | | - Age ≥ 18 yrs
- Level C1-C7
AIS A, B, C- ≥ 6 months
- NOT have an active implantable medical device such as a pacemaker or defibrillator
| Recruiting | 20 | NA | Technology | Arm/hand function | - Grasp and Release Test (GRT)
| 1 year | 01 January 2025 | 25 September 2024 | 1 | |
| NCT06706284 | Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes | The University of Texas Health Science Center at San Antonio | | - Age 18 - 70 yrs
- Level C2-L2
AIS A, B, C, D- ≥ 12 months
- be diagnosed with 2 diabetes (T2DM)
| Recruiting | 50 | PHASE4 | Drug | General health | | 24 weeks | 11 April 2025 | 26 November 2024 | 2 | |
| NCT06351111 | Vagus Nerve Stimulation (VNS) in Spinal Cord Injury (SCI) Adaptive Follow-On Study | The University of Texas at Dallas | | - Age 18 - 64 yrs
- Level C1-C8
AIS - ≥ 12 months
- have completed phase 2 of the SCI EFS study (NCT04288245)
| By invitation | 20 | NA | Technology | General health | - 10 Meter Walking Test (10 MWT)
- 6-Minute Walk Test (6MWT)
- Adverse Events (AEs)
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Berg Balance Scale (BBS)
- Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)
- Jebsen Hand Function Test (JHFT)
- Neurogenic Bladder Symptom Score
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 15 weeks | 29 August 2024 | 08 April 2024 | 2 | |
| NCT06541197 | The Effect of Functional Electrical Stimulation Cycling Ergometry in Addition to Robotic Rehabilitation | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | | - Age 18 - 65 yrs
- Level C1-S5
AIS C, D- ≥ 6 months
- NOT have a metallic implants in the lower extremities.
- NOT have a cardiac pacemaker.
| Ended | 38 | NA | Rehabilitation | Standing/walking/mobility | - 10 Meter Walking Test (10 MWT)
- 2 Minute Walk Test
- American Spinal Injury Association Impairment Scale (AIS): International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Spinal Cord Independence Measure (SCIM)
- Timed Up and Go Test (TUG)
- Walking Index for Spinal Cord Injury (WISCI) and WISCI II
| 4 weeks | 01 November 2024 | 07 August 2024 | 2 | |
