The Therapeutic Effect of Betaine in Syringomyelia

Drug

Arm/hand function

Online since 13 August 2024, updated today

About this trial

This trial is enrolling 30 participants with refractory syringomyelia to test the effect of betaine on symptoms. Betaine is a drug used to manage or stabilize the balance of water within cells and tissues. If included, participants will receive either 50mg/kg of betaine or a placebo drug for 12 weeks. Final testing of sensory and motor function will be performed after 3 months.

Included participants

Gender

All

Age

18 - 80 years

Injury level

C1 - S5

Severity (AIS)?

Time since injury

All

Healthy volunteers

C1-S5

Additionally, participants must

NOT have transplanted organs

NOT have a history of psychiatric diseases or seizures

NOT have a history of cardiovascular disease

What’s involved

Type

Drug

Details

- Participants will receive either 50mg/kg of betaine or a placebo drug for 12 weeks. - Betaine is an osmotic homeostasis-related drug used to manage or stabilize the balance of water and solutes within cells and tissues. - Final testing of sensory and motor function will be performed after 3 months.

Potential benefits

Main benefits

Arm/hand function

Additional benefits

Bladder health/function

General health

Pain

Sensory function

Standing/walking/mobility

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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