| NCT06847295 | Epidural Electrical Stimulation to Restore Standing and Walking in Patients With Chronic Paralysis Due to Spinal Cord Injury: A Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive Rehabilitation | University of Sao Paulo General Hospital | | - Age 18 - 50 yrs
- Level C7-T10
AIS A, B- ≥ 6 months
- NOT currently use electronic devices such as baclofen pumps or cardiac pacemakers
| Recruiting | 10 | NA | Surgery | Standing/walking/mobility | - Ashworth and Modified Ashworth Scale (MAS)
- Beck Depression Inventory (BDI)
- Berg Balance Scale (BBS)
- Brief Pain Inventory (BPI)
- Fugl-Meyer Assessment (FMA)
- Neurogenic Bladder Symptom Score
- Neurogenic Bowel Dysfunction Score (NBD or NBDS)
- World Health Organization Quality of Life- BREF (WHOQOL-BREF)
| 15 months | 28 January 2022 | 26 February 2025 | 1 | |
| NCT07364773 | Enhancing Rehabilitation Participation in Patients With SCI/D Using Motivational Interviewing | Shirley Ryan AbilityLab | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
- be receiving inpatient rehabilitation at one of the three study sites
| Recruiting | 180 | NA | Rehabilitation | General health | - Spinal Cord Injury Functional Index
| 1 year | 01 November 2025 | 23 January 2026 | 3 | |
| NCT07375745 | Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury | Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal | | - Age ≥ 16 yrs
- Level C1-L2
AIS A, B, C, D- 7 days - 6 months
- NOT have a pacemaker
| Recruiting soon | 40 | NA | Technology | Standing/walking/mobility | - American Spinal Injury Association Impairment Scale (AIS)
- Ashworth and Modified Ashworth Scale (MAS)
- International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
- Modified Functional Reach Test (mFRT)
- Motor Evoked Potentials (MEPs)
- Surface Electromyography (sEMG)
| 2 months | 01 July 2026 | 29 January 2026 | 1 | |
| NCT07167680 | Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters | University of Illinois at Urbana-Champaign | | - Age ≥ 18 yrs
- Level C1-S5
AIS - All
- Be unable to walk 25 feet or more
- Have experienced at least 1 fall in the past 3 years
| Recruiting soon | 120 | NA | Psychosocial/other | General health | - System Usability Scale (SUS)
- Wheelchair Skills Test (WST, 4.1)
| 14 weeks | 01 September 2025 | 11 September 2025 | 1 | |
| NCT07429305 | Combined Tibial Nerve Stimulation and Standing for People With SCI | University of British Columbia | | - Age ≥ 19 yrs
- Level C7-T10
AIS A, B, C, D- ≥ 12 months
- NOT have an implanted metallic or electronic device (e.g. pace maker, nerve stimulator)
| Recruiting | 12 | NA | Technology | Bladder health/function | - Adverse Events (AEs)
- Feasibility
- Incontinence Quality of Life Questionnaire (I-QOL)
- Neurogenic Bladder Symptom Score
| 8 months | 02 April 2026 | 24 February 2026 | 1 | |
| NCT07433959 | Neuromodulation to Improve Grasping Function After SCI | State University of New York at Buffalo | | - Age 18 - 75 yrs
- Level C1-C8
AIS - ≥ 12 months
- NOT have a metal plate in the skull
- Not have a history of seizures
| Recruiting | 54 | NA | Technology | General health | - Hand-Held Myometery / Dynamometry
- Motor Evoked Potentials (MEPs)
- Toronto Rehabilitation Institute Hand Function Test
| 4 weeks | 01 April 2026 | 25 February 2026 | 1 | |
