Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury
About this trial
This trial is enrolling 16 participants with chronic spinal cord injury to test the effect of transcutaneous) spinal stimulation (TSS) on muscle stiffness and spasms. TSS is a non-surgical technique for stimulating the spinal cord via surface electrodes on the lower back and abdomen to modify spinal cord function. If included, participants will undergo 6 sessions of stimulation at two frequencies (50 and 100 Hz), in combination with or without a single oral dose of baclofen, tizanidine, or a placebo. Final testing of spasticity will be performed after 5 weeks.
Included participants
What’s involved
Type
Details
- Participants will undergo 6 sessions of transcutaneous spinal stimulation at different frequencies (50 and 100 Hz) and in combination with a dose of baclofen, tizanidine, or a placebo. - Transcutaneous spinal stimulation is a technique for stimulating the spinal cord via surface stimulation over the lower back and abdomen to modify spinal cord function. - Final testing of spasticity will be performed after 5 weeks.
Potential benefits
Main benefits
Spasticity
Additional benefits
General health
Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more- Trial recruitment status
- Recruiting
- Trial start date
- 1 Mar 2024
- Organisation
- University of Mississippi Medical Center
- Trial recruitment status
- Recruiting
- Trial start date
- 1 Mar 2024
- Organisation
- University of Mississippi Medical Center
About this trial
Included participants
What’s involved
Potential benefits
Wings for Life supports SCITrialsFinder
Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.
Learn more