Neural Plasticity and Motor Recovery After Early and Intensive Upper Extremity Motor Training in People With c-SCI

Rehabilitation
Arm/hand function
Online since 4 January 2024, updated 57 days ago

About this trial

This trial is enrolling 40 individuals with acute cervical spinal cord injury to test the effect of early and intensive upper limb motor training on arm and hand function. If included, participants will receive either a) 10 weeks of standard physical therapy; or b) standard therapy along with 12 hours of intensive motor training per week for 10 weeks. Final testing of upper limb function will be performed 6 months after training completion. Investigators will also measure potential nerve circuit changes (neuroplasticity).

Included participants

Gender
All
Age
16 - 90 years
Injury level
C5 - C8
  • Severity (AIS)?
  • AIS-A
    Time since injury
    ≤ 10 weeks
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    C5-C8
    Additionally, participants must
    NOT have metal implants in the brain, defibrillator, or pacemaker
    NOT have epilepsy

    What’s involved

    Type

    Rehabilitation

    Details

    - Participants will receive either standard physical therapy or standard therapy along with 12 hours of intensive upper-limb motor training per week for a total of 10 weeks. - Final testing of arm and hand function will be performed 6 months after training completion.

    Potential benefits

    Main benefits

    Arm/hand function

    Additional benefits

    General health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 5 Oct 2023
    • Organisation
    • Hasselt University
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 5 Oct 2023
    • Organisation
    • Hasselt University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more