Neural Plasticity and Motor Recovery After Early and Intensive Upper Extremity Motor Training in People With c-SCI

Rehabilitation

Arm/hand function

Online since 4 January 2024, updated 335 days ago

About this trial

This trial is enrolling 40 individuals with acute cervical spinal cord injury to test the effect of early and intensive upper limb motor training on arm and hand function. If included, participants will receive either a) 10 weeks of standard physical therapy; or b) standard therapy along with 12 hours of intensive motor training per week for 10 weeks. Final testing of upper limb function will be performed 6 months after training completion. Investigators will also measure potential nerve circuit changes (neuroplasticity).

Included participants

Gender

All

Age

16 - 90 years

Injury level

C5 - C8

Severity (AIS)?

AIS-A

Time since injury

≤ 10 weeks

Injury type

Traumatic

Non-traumatic

Healthy volunteers

C5-C8

Additionally, participants must

NOT have metal implants in the brain, defibrillator, or pacemaker

NOT have epilepsy

What’s involved

Type

Rehabilitation

Details

- Participants will receive either standard physical therapy or standard therapy along with 12 hours of intensive upper-limb motor training per week for a total of 10 weeks. - Final testing of arm and hand function will be performed 6 months after training completion.

Potential benefits

Main benefits

Arm/hand function

Additional benefits

General health

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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