Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury

Technology
General health
Online since 30 November 2023, updated 139 days ago

About this trial

This trial is enrolling 36 individuals with chronic spinal cord injury to test the combination of non-invasive spinal cord transcutaneous stimulation (scTS) with respiratory training (RT) on lung function and breathing ability. scTS is a technique for stimulating the spinal cord via surface electrodes to modify spinal cord function. Respiratory training includes exercises to inhale or exhale against a pressure load. If included, participants will receive 80 sessions of either RT alone, scTS alone, or a combination of RT + scRT over 16 weeks. Final testing of lung function and breathing will be performed after 34 weeks.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C1 - T5
  • Severity (AIS)?
  • AIS-A
    AIS-B
    Time since injury
    ≥ 12 months
    Healthy volunteers
    No
    C1-T5
    Additionally, participants must
    at least 15% deficit in pulmonary function
    not be ventilator dependent

    What’s involved

    Type

    Technology

    Details

    - Participants will receive 80 sessions of either respiratory training (RT), spinal cord Transcutaneous Stimulation (scTS), or a combination of RT + scTS. - scTS is a technique that applies electrical stimulation through the skin to the spinal cord to modify spinal cord function. - Final testing will be performed after 34 weeks..

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 10 Sep 2023
    • Organisation
    • University of Louisville
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 10 Sep 2023
    • Organisation
    • University of Louisville

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more