Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury

Technology
General health
Online since 18 October 2023, updated 130 days ago

About this trial

This trial is enrolling individuals with chronic spinal cord injuries (C3-T6) to test the effect of skin-surface (transcutaneous) spinal cord stimulation (TSCS) on the ability to perform moderate exercise and regulate core body temperature. TSCS is a technique for stimulating the spinal cord via surface electrodes to modify spinal cord function. If included, participants will undergo two study visits that last about 3-4 hours each. While using an arm bicycle, each will receive two therapy sessions: TSCS or sham TSCS, both while seated in a room with neutral temperature (80°F) and in a cool room (64°F). Final testing of endurance, body temperature, and heart rate will be performed 90 minutes after the intervention.

Included participants

Gender
All
Age
≥ 18 years
Injury level
C3 - T6
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    Time since injury
    ≥ 1 year
    Healthy volunteers
    No
    C3-T6
    Additionally, participants must
    NOT have a history of seizures
    NOT have diabetes

    What’s involved

    Type

    Technology

    Details

    - participants will undergo 2 study visits that last about 3-4 hours each. - They will receive either 1) TSCS or 2) sham TSCS while seated in a room with neutral temperature (80°F) and in a cool room (64°F). - Final testing of endurance, body temperature, and heart rate will be performed 90 minutes after the intervention.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Arm/hand function

    Pain

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 30 Jul 2023
    • Organisation
    • James J. Peters Veterans Affairs Medical Center
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 30 Jul 2023
    • Organisation
    • James J. Peters Veterans Affairs Medical Center

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more