tSCS + EksoGT in SCI Patients

Technology
Standing/walking/mobility
Online since 27 October 2023, updated 121 days ago

About this trial

This pilot trial is enrolling 6 individuals with chronic, incomplete thoracic spinal cord injury to test the effect of skin-surface (transcutaneous) spinal cord stimulation (tSCS) combined with robotic gait training (RGT) on functional mobility. RGT utilizes an exoskeleton (EksoGT), an externally worn powered robotic device to assist movement. tSCS is a technique for stimulating the spinal cord via surface electrodes to modify spinal cord function. If included, participants will undergo 2 phases of training in random order, separated by 1 week in between phases. One phase consists of 16 sessions of RGT and 8-10 weeks of conventional physical therapy. The second phase is the same with 45 minutes of tSCS applied during RGT. Final testing of functional mobility will be performed one week after each phase and an overall satisfaction survey will be performed at week 18.

Included participants

Gender
All
Age
21 - 65 years
Injury level
T1 - L1
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    6 months - 2 years
  • Injury type
  • Traumatic

    Healthy volunteers
    No
    T1-L1

    What’s involved

    Type

    Technology

    Details

    - Participants will undergo 2 phases in random order. - One phase consists of 16 sessions of robotic gait training (RGT) and 8-10 weeks of conventional physiotherapy. - During RGT training, participants will walk with EksoGT for gait training, an externally worn powered robotic device to assist movement. - The other phase will be the same with 45 minutes of tSCS applied during RGT. - tSCS is a technique for stimulating the spinal cord via surface stimulation on the skin to modify spinal cord function. - Final testing of functional mobility will be performed one week after each phase and an overall satisfaction survey will be performed at week 18.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Mental health

    Sensory function

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Oct 2023
    • Organisation
    • National University Hospital, Singapore
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Oct 2023
    • Organisation
    • National University Hospital, Singapore

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more