The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

Technology
General health
Online since 16 August 2023, updated 187 days ago

About this trial

This trial is enrolling 5 individuals with chronic spinal cord injuries T6 and above to test the effect of skin surface (transcutaneous) spinal cord stimulation (tSCS) on blood pressure (i.e., orthostatic hypotension; a drop in blood pressure when moving from lying flat on your back to an upright position). tSCS is a technique for stimulating the spinal cord to modify spinal cord function. If included, participants will undergo orthostatic tests (lying on a table that starts out flat, then tilts upward up to 70 degrees), with and without stimulation; changes in blood pressure will be measured. Final testing will be performed after 6 weeks.

Included participants

Gender
All
Age
18 - 75 years
Injury level
C1 - T6
  • Severity (AIS)?
  • AIS-A
    AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 6 months
    Healthy volunteers
    No
    C1-T6
    Additionally, participants must
    NOT be ventilator dependent
    NOT have other implanted pacemaker device

    What’s involved

    Type

    Technology

    Details

    Participants will undergo orthostatic tests (lying on a table that starts out flat, then tilts upward up to 70 degrees), with and without stimulation. Changes in blood pressure will be evaluated.

    Potential benefits

    Main benefits

    General health

    Additional benefits

    Mental health

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 May 2023
    • Organisation
    • Kessler Foundation
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 May 2023
    • Organisation
    • Kessler Foundation

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more