The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

Technology

General health

Online since 16 August 2023, updated 335 days ago

About this trial

This trial is enrolling 5 individuals with chronic spinal cord injuries T6 and above to test the effect of skin surface (transcutaneous) spinal cord stimulation (tSCS) on blood pressure (i.e., orthostatic hypotension; a drop in blood pressure when moving from lying flat on your back to an upright position). tSCS is a technique for stimulating the spinal cord to modify spinal cord function. If included, participants will undergo orthostatic tests (lying on a table that starts out flat, then tilts upward up to 70 degrees), with and without stimulation; changes in blood pressure will be measured. Final testing will be performed after 6 weeks.

Included participants

Gender

All

Age

18 - 75 years

Injury level

C1 - T6

Severity (AIS)?

AIS-A

AIS-B

AIS-C

AIS-D

Time since injury

≥ 6 months

Healthy volunteers

C1-T6

Additionally, participants must

NOT be ventilator dependent

NOT have other implanted pacemaker device

What’s involved

Type

Technology

Details

Participants will undergo orthostatic tests (lying on a table that starts out flat, then tilts upward up to 70 degrees), with and without stimulation. Changes in blood pressure will be evaluated.

Potential benefits

Main benefits

General health

Additional benefits

Mental health and psychosocial factors

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

Wings for Life supports SCITrialsFinder

Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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