Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity

Technology
Standing/walking/mobility
Online since 28 August 2023, updated 175 days ago

About this trial

This trial is enrolling individuals with chronic spinal cord injuries at the cervical or thoracic level to test the effect of skin-surface (transcutaneous) electrical spinal cord stimulation (SCS) on arm and leg function. Transcutaneous SCS is a non-invasive technique for stimulating the spinal cord via surface electrodes to modify spinal cord function. If included, participants will undergo two phases of stimulation, both done while performing functional task exercises: 15 sessions of open-loop SCS (fixed stimulation parameters) and 15 sessions of closed-loop SCS (stimulation parameters continuously revised in real-time based upon exact movements of participant as captured by wearable sensors). These stimulation sessions will be combined with exercise therapy for upper and/or lower extremity function. Final testing of arm and leg function will be performed after 3 months.

Included participants

Gender
All
Age
18 - 55 years
Injury level
C2 - T10
  • Severity (AIS)?
  • AIS-B
    AIS-C
    AIS-D
    Time since injury
    ≥ 12 months
    Healthy volunteers
    No
    C2-T10

    What’s involved

    Type

    Technology

    Details

    - Participants will receive 30 sessions of transcutaneous SCS while performing exercises (Functional Task Practice (FTP)) - Final testing of arm and leg function will be performed after 3 months.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    General health

    Sensory function

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Active
    • Trial start date
    • 10 Feb 2022
    • Organisation
    • Thomas Jefferson University
    • Trial recruitment status
    • Active
    • Trial start date
    • 10 Feb 2022
    • Organisation
    • Thomas Jefferson University

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more