Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury

Surgery

Arm/hand function

Online since 2 May 2023, updated today

About this trial

This trial is enrolling individuals with chronic cervical spinal cord injuries to test the effect of nerve transfer surgery on arm and hand function. Nerve transfer surgery relocates an intact nerve to a target nerve attached to a muscle that has significant weakness or paralysis. If included, participants will receive nerve transfer surgery. Recipients will be compared with matched individuals who do not receive nerve transfer surgery (control group). Final testing of arm and hand function will be performed after 2 years.

Included participants

Gender

All

Age

18 - 70 years

Injury level

C5 - C8

Severity (AIS)?

AIS-A

AIS-B

Time since injury

6 months - 9 months

Injury type

Traumatic

Healthy volunteers

C5-C8

What’s involved

Type

Observational

Details

- Surgery to transfer an intact nerve to a target nerve attached to a muscle that has significant weakness or paralysis. - Participants that decide to not receive nerve transfer surgery will be recruited as the control group. - Final testing of arm and hand function will be performed after 2 years.

Potential benefits

Main benefits

Arm/hand function

Additional benefits

Mental health

Pain

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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