NEUROMOdulation Pain Therapy in Combination With Intensive Physiotherapy

Technology
Standing/walking/mobility
Online since 28 August 2023, updated 175 days ago

About this trial

This trial is enrolling individuals with spinal cord injuries to test the effect of epidural spinal cord stimulation (eSCS) in combination with physiotherapy on walking function. eSCS is a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord. If included, participants will undergo surgery to implant the electrodes. In addition to eSCS, all participants will undergo physiotherapy 4 hours per day for 1 month. Lower limb mobility will be assessed at 2 weeks, 6 weeks, 6 and 12 months post treatment.

Included participants

Gender
All
Age
18 - 60 years
Injury level
T1 - S5
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    All
  • Injury type
  • Traumatic

    Non-traumatic

    Healthy volunteers
    No
    T1-S5
    Additionally, participants must
    Have a spinal cord lesion resulting in spastic paraparesis (weakness of the lower extremities)
    Not have any other neurological condition

    What’s involved

    Type

    Technology

    Details

    - surgery for implanting the electrodes next to the spinal cord - epidural spinal cord stimulation - physiotherapy 4 hours per day, for 1 month.

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    Arm/hand function

    General health

    Mental health

    Pain

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Oct 2024
    • Organisation
    • Charles University, Czech Republic
    • Trial recruitment status
    • Recruiting soon
    • Trial start date
    • 1 Oct 2024
    • Organisation
    • Charles University, Czech Republic

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more