NEUROMOdulation Pain Therapy in Combination With Intensive Physiotherapy

Technology

Standing/walking/mobility

Online since 28 August 2023, updated 323 days ago

About this trial

This trial is enrolling individuals with spinal cord injuries to test the effect of epidural spinal cord stimulation (eSCS) in combination with physiotherapy on walking function. eSCS is a technique for stimulating the spinal cord with an implanted electrode placed next to the spinal cord. If included, participants will undergo surgery to implant the electrodes. In addition to eSCS, all participants will undergo physiotherapy 4 hours per day for 1 month. Lower limb mobility will be assessed at 2 weeks, 6 weeks, 6 and 12 months post treatment.

Included participants

Gender

All

Age

18 - 60 years

Injury level

T1 - S5

Severity (AIS)?

AIS-C

AIS-D

Time since injury

All

Injury type

Traumatic

Non-traumatic

Healthy volunteers

T1-S5

Additionally, participants must

Have a spinal cord lesion resulting in spastic paraparesis (weakness of the lower extremities)

Not have any other neurological condition

What’s involved

Type

Technology

Details

- surgery for implanting the electrodes next to the spinal cord - epidural spinal cord stimulation - physiotherapy 4 hours per day, for 1 month.

Potential benefits

Main benefits

Standing/walking/mobility

Additional benefits

Arm/hand function

General health

Mental health and psychosocial factors

Pain

Spasticity

Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

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Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

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