Effects of Intermittent Hypoxia in Upper and Lower Limb Functions in Persons With Incomplete Spinal Cord Injury

About this trial

This trial is enrolling individuals with incomplete spinal cord injuries for at least 3 months (at level C4 or below) to test the effect of acute intermittent hypoxia (AIH) on upper and lower limb function. AIH involves repeatedly breathing air with low oxygen content for brief periods, alternating with breathing room air with normal oxygen content. If included, participants will undergo an intervention 3 times/week for a period of 4 weeks of either: 1) AIH (9% oxygen) alternating with normal air (21% oxygen); or 2) a sham treatment, normal air alternating with normal air. Assessments include upper and lower limb motor function, balance, quality of life, and disability.