Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity

Technology
Standing/walking/mobility
Online since 19 October 2022, updated 635 days ago

About this trial

This trial is enrolling individuals with sub-acute (3 months post injury) to chronic incomplete spinal cord injuries at the T12 level or above to test the effect of moderate-intensity motor skill training (MST) combined with skin-surface (transcutaneous) spinal stimulation (TSS) on walking function. TSS is a technique for stimulating the spinal cord via skin surface electrodes to modify spinal cord function. If included, participants will receive 6 sessions over a 2 week span of either: 1) MST + active TSS; 2) MST + sham (inactive) TSS; or 3) cyclic aerobic exercise (CAX) + active TSS. Final testing of walking function will be performed after 27 days.

Included participants

Gender
All
Age
18 - 70 years
Injury level
C1 - T12
  • Severity (AIS)?
  • AIS-C
    AIS-D
    Time since injury
    ≥ 12 months
    Healthy volunteers
    No
    C1-T12
    Additionally, participants must
    be able to stand for at least 5 minutes (with or without an assistive device)
    be able to move each leg independently for at least three steps
    be able to rise from sit to stand with no more than moderate assistance from one person

    What’s involved

    Type

    Technology

    Details

    - participants will receive 6 session over a 2 week span of either 1) MST + active TSS, 2) MST + sham TSS, or 3) cyclic aerobic exercise (CAX) + active TSS - Final testing of walking function will be performed after 27 days

    Potential benefits

    Main benefits

    Standing/walking/mobility

    Additional benefits

    General health

    Spasticity

    Good to know: Potential benefits are defined as outcomes that are being measured during and/or after the trial.

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more

    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Mar 2022
    • Organisation
    • Shepherd Center, Atlanta GA
    • Trial recruitment status
    • Recruiting
    • Trial start date
    • 1 Mar 2022
    • Organisation
    • Shepherd Center, Atlanta GA

    Wings for Life supports SCITrialsFinder

    Wings for Life has proudly initiated, led and funded the new version of the SCI Trials Finder website. Wings for Life aims to find a cure for spinal cord injuries. The not-for-profit foundation funds world-class scientific research and clinical trials around the globe.

    Learn more